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K Tullus

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Articles 86
Citations 815
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Recent Articles
1.
Smith E, Aggarwal A, Ainsworth J, Al-Abadi E, Avcin T, Bortey L, et al.
Clin Immunol . 2024 Apr; 263:110214. PMID: 38604255
Objective: To derive childhood-onset SLE (cSLE) specific remission definitions for future treat-to-target (T2T) trials, observational studies, and clinical practice. Methods: The cSLE International T2T Task Force conducted Delphi surveys exploring...
2.
Smith E, Aggarwal A, Ainsworth J, Al-Abadi E, Avcin T, Bortey L, et al.
Clin Immunol . 2023 Mar; 250:109296. PMID: 36934849
Objective: To achieve a consensus-based definition of Low Disease Activity (LDA) for use in cSLE trials. Methods: The International cSLE T2T Task Force, comprising of paediatric rheumatologists/nephrologists, and adult rheumatologists...
3.
Smith E, Eleuteri A, Goilav B, Lewandowski L, Phuti A, Rubinstein T, et al.
Clin Immunol . 2018 Nov; 198:71-78. PMID: 30391651
Background: A urine 'biomarker panel' comprising alpha-1-acid-glycoprotein, ceruloplasmin, transferrin and lipocalin-like-prostaglandin-D synthase performs to an 'excellent' level for lupus nephritis identification in children cross-sectionally. The aim of this study was...
4.
Patel M, Oni L, Midgley A, Smith E, Tullus K, Marks S, et al.
Lupus . 2016 Feb; 25(9):1040-4. PMID: 26854079
Background: Juvenile-onset systemic lupus erythematous (JSLE) is a debilitating condition that frequently involves the kidneys (lupus nephritis; LN). Tumour necrosis factor alpha (TNF-α), an important pro-inflammatory cytokine, is expressed locally...
5.
Watson L, Beresford M, Maynes C, Pilkington C, Marks S, Glackin Y, et al.
Lupus . 2014 Aug; 24(1):10-7. PMID: 25117653
Background: B cells drive antibody formation and T cell activation. This study aimed to describe the clinical indications, efficacy and adverse events (AEs) for the B-cell depleting agent, rituximab, in...
6.
Watson L, Tullus K, Marks S, Holt R, Pilkington C, Beresford M
J Clin Immunol . 2012 Jun; 32(5):1019-25. PMID: 22648459
Purpose: Sphingosine-1-phosphate (S1P) is an active sphingolipid with chemotactic abilities and has been linked to inflammatory mediators and autoimmune disease. The aim of this study was to assess whether children...
7.
Watson L, Midgley A, Pilkington C, Tullus K, Marks S, Holt R, et al.
Lupus . 2011 Dec; 21(5):496-501. PMID: 22147846
A higher proportion of patients with juvenile-onset systemic lupus erythematosus (JSLE) will have renal involvement compared with adult-onset disease, some progressing to renal failure in adulthood. Histological examination is the...
8.
Mori R, Yonemoto N, Fitzgerald A, Tullus K, Verrier-Jones K, Lakhanpaul M
Acta Paediatr . 2010 Jan; 99(4):581-4. PMID: 20055779
Background: Prompt diagnosis of urinary tract infection (UTI) in children is needed to initiate treatment but is difficult to establish without urine testing, and reliance on culture leads to delay....
9.
Waters A, Pappworth I, Marchbank K, Bockenhauer D, Tullus K, Pickering M, et al.
Am J Transplant . 2009 Dec; 10(1):168-72. PMID: 19951285
Factor H (CFH) autoantibodies are associated with atypical hemolytic uremic syndrome (aHUS). Peritransplantation plasma exchange therapy and intensification of immunosuppression, with adjuvant use of anti-CD20 monoclonal antibodies has recently been...
10.
Resic-Lindehammer S, Larsson K, Ortqvist E, Carlsson A, Cederwall E, Cilio C, et al.
Acta Diabetol . 2008 Sep; 45(4):231-5. PMID: 18769865
The aim of this study was to compare the frequency of human leukocyte antigen (HLA) genotypes in 1-18-year-old patients with type 1 diabetes newly diagnosed in 1986-1987 (n = 430),...