K T Lappegard
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Explore the profile of K T Lappegard including associated specialties, affiliations and a list of published articles.
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15
Citations
92
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Recent Articles
1.
Landsem A, Fure H, Krey Ludviksen J, Christiansen D, Lau C, Mathisen M, et al.
Clin Exp Immunol
. 2018 Nov;
196(1):97-110.
PMID: 30444525
There is a close cross-talk between complement, Toll-like receptors (TLRs) and coagulation. The role of the central complement component 5 (C5) in physiological and pathophysiological hemostasis has not, however, been...
2.
Lappegard K, Bjornstad H, Mollnes T, Hovland A
Scand J Immunol
. 2015 Jun;
82(3):191-8.
PMID: 26099323
Congestive heart failure is associated with increased levels of several inflammatory mediators, and animal studies have shown that infusion of a number of cytokines can induce heart failure. However, several...
3.
Lappegard K, Hovland A, Pop G, Mollnes T
Scand J Immunol
. 2013 May;
78(2):112-9.
PMID: 23672430
Atrial fibrillation is highly prevalent, and affected patients are at an increased risk of a number of complications, including heart failure and thrombo-embolism. Over the past years, there has been...
4.
Hovland A, Lappegard K, Mollnes T
Scand J Immunol
. 2012 Jun;
76(3):229-36.
PMID: 22670805
Low-density lipoprotein (LDL) apheresis is an extracorporeal treatment modality used in high-risk patients when LDL cholesterol levels cannot be reduced adequately with medication. The treatment is highly effective, but could...
5.
Lappegard K, Bergseth G, Riesenfeld J, Pharo A, Magotti P, Lambris J, et al.
J Biomed Mater Res A
. 2007 Dec;
87(1):129-35.
PMID: 18085644
Exposing blood to an artificial surface results in a systemic inflammatory response, including cytokine release and complement activation. We studied the artificial surface-induced inflammation in human whole blood using an...
6.
Troseid M, Lappegard K, Mollnes T, Arnesen H, Seljeflot I
Scand J Clin Lab Invest
. 2005 Aug;
65(4):283-90.
PMID: 16076683
Objective: Inflammation plays an essential role in the atherosclerotic process. Cellular adhesion molecules (CAMs) such as E-selectin, intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) are involved in...
7.
Lappegard K, Justad G, Prytz J, Manhenke C
J Intern Med
. 2005 May;
257(6):558-60.
PMID: 15910560
During the course of an inflammatory process in the thoracic part of the spinal cord, a previously healthy male suffered two myocardial infarctions in separate coronary territories. A coronary angiogram...
8.
Lappegard K, Hvassing T, Mollnes T
Scand J Immunol
. 2004 Jul;
60(1-2):178-83.
PMID: 15238087
Statin drugs prevent coronary heart disease through anti-inflammatory mechanisms in addition to the well-known reduction of low-density lipoproteins. The complement system plays an essential role in the inflammatory response and...
9.
Aukrust P, Gullestad L, Lappegard K, Ueland T, Aass H, Wikeby L, et al.
Circulation
. 2001 Sep;
104(13):1494-500.
PMID: 11571242
Background: Increasing evidence implicates innate immunity in the pathogenesis of congestive heart failure (CHF). In the present study, we examined the possible role of complement, an important part of innate...
10.
Lappegard K, Aass H
Tidsskr Nor Laegeforen
. 2001 Jul;
120(20):2395-6.
PMID: 11475223
Background: Fabry's disease is an X-linked inborn error of metabolism. The patients lack or have very low activity of the enzyme alpha-galactosidase A. This results in deposition of sphingolipids in...