K Sathasivam
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Explore the profile of K Sathasivam including associated specialties, affiliations and a list of published articles.
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12
Citations
1592
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Recent Articles
1.
Sashi Kumar V, Paul V, Sathasivam K
J Perinatol
. 2016 Dec;
36(s3):S32-S36.
PMID: 27924105
The care of small and sick neonates requires biomedical technologies, such as devices that can keep babies warm (radiant warmers and incubators), resuscitate (self-inflating bags), track growth (weighing scales), treat...
2.
Olliaro P, Nair N, Sathasivam K, Mansor S, Navaratnam V
BMC Pharmacol
. 2002 Feb;
1:12.
PMID: 11835690
Background: Artesunate is a commonly used antimalarial drug derived from artemisinin. It is rapidly converted to dihydroartemisinin. Little is known on this conversion in the GI tract and blood, and...
3.
Sathasivam K, Woodman B, Mahal A, BERTAUX F, Wanker E, Shima D, et al.
Hum Mol Genet
. 2001 Nov;
10(21):2425-35.
PMID: 11689489
Huntington's disease (HD) is a progressive neurological disorder caused by a CAG/polyglutamine repeat expansion. We have previously generated the R6/2 mouse model that expresses exon 1 of the human HD...
4.
Waelter S, Scherzinger E, Hasenbank R, Nordhoff E, Lurz R, Goehler H, et al.
Hum Mol Genet
. 2001 Sep;
10(17):1807-17.
PMID: 11532990
The huntingtin interacting protein (HIP1) is enriched in membrane-containing cell fractions and has been implicated in vesicle trafficking. It is a multidomain protein containing an N-terminal ENTH domain, a central...
5.
Davies S, Sathasivam K, Hobbs C, Doherty P, Mangiarini L, Scherzinger E, et al.
Methods Enzymol
. 1999 Oct;
309:687-701.
PMID: 10507055
No abstract available.
6.
Sathasivam K, Hobbs C, Mangiarini L, Mahal A, Turmaine M, Doherty P, et al.
Philos Trans R Soc Lond B Biol Sci
. 1999 Aug;
354(1386):963-9.
PMID: 10434294
Huntington's disease (HD) is an inherited neurodegenerative disorder caused by a CAG-polyglutamine repeat expansion. A mouse model of this disease has been generated by the introduction of exon 1 of...
7.
Sathasivam K, Hobbs C, Turmaine M, Mangiarini L, Mahal A, BERTAUX F, et al.
Hum Mol Genet
. 1999 Apr;
8(5):813-22.
PMID: 10196370
Huntington's disease (HD) is one of a class of inherited progressive neurodegenerative disorders that are caused by a CAG/polyglutamine repeat expansion. We have previously generated mice that are transgenic for...
8.
Sathasivam K, Baxendale S, Mangiarini L, BERTAUX F, Hetherington C, Kanazawa I, et al.
Hum Mol Genet
. 1997 Nov;
6(12):2141-9.
PMID: 9328479
The puffer fish ( Fugu rubripes ) has a compact genome of 400 Mbp which is approximately 7.5-fold smaller than the human genome. It contains a similar number of genes...
9.
Notarianni E, Laurie S, Ng A, Sathasivam K
Int J Dev Biol
. 1997 Jun;
41(3):537-40.
PMID: 9240573
The derivation of murine, embryonic stem cells, and their use in the generation of transgenic mice, are well-established procedures. Application of these methodologies to non-murine species, however, remains to be...
10.
Sathasivam K, Amaechi I, Mangiarini L, Bates G
Hum Genet
. 1997 May;
99(5):692-5.
PMID: 9150744
The Huntington's disease mutation has been identified as a CAG/polyglutamine repeat expansion in a large gene of unknown function. In order to develop the transgenic systems necessary to uncover the...