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K R Rajalekshmy

Explore the profile of K R Rajalekshmy including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 53
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Recent Articles
1.
Radhakrishnan V, Thampy C, Ganesan P, Rajendranath R, Ganesan T, Rajalekshmy K, et al.
Indian J Hematol Blood Transfus . 2016 Jul; 32(3):257-61. PMID: 27429516
There is paucity of data in pediatric Acute Myeloid Leukemia (AML) from developing countries. We analyzed the outcomes of 65 consecutive patients with pediatric AML treated at our centre from...
2.
Rajkumar T, Gopal G, Selvaluxmi G, Rajalekshmy K
Indian J Biochem Biophys . 2013 Aug; 42(5):271-8. PMID: 23923534
In the present study, an attempt was made to identify genes involved in radiation response in cervix carcinoma. Differential display technique was used to study the expression profiles of tumour...
3.
Rajalekshmy K, Abitha A, Anuratha N, Sagar T
Indian J Cancer . 2011 Sep; 48(3):310-5. PMID: 21921330
Background: Pediatric acute lymphoblastic leukemia (ALL) is a biologically heterogeneous disease and socioeconomic and environmental factors are considered to be an important determinant of its immunophenotype. The aim of this...
4.
Suneetha K, Nancy K, Rajalekshmy K, Rama R, Sagar T, Rajkumar T
Indian J Med Paediatr Oncol . 2011 Jul; 32(1):25-9. PMID: 21731212
Background: Polymorphisms in the drug-metabolizing enzymes are found to be associated with the inter-individual variation in response to a particular drug. Glutathione S-transferases (GSTs) are involved in the metabolism of...
5.
Suneetha K, Nancy K, Rajalekshmy K, Sagar T, Rajkumar T
Asian Pac J Cancer Prev . 2009 Mar; 9(4):733-6. PMID: 19256768
Acute lymphoblastic leukaemia (ALL) is the most common pediatric malignancy worldwide. The origin of this disease may be explained by a combination of genetic and environmental factors. Glutathione-s-transferases are a...
6.
Sudhakar N, Nirmala K, Rajalekshmy K, Rajkumar T
Asian Pac J Cancer Prev . 2008 Apr; 9(1):127-30. PMID: 18439091
Background: The incidence of T-cell acute lymphoblastic leukemia (T-ALL) in South India is very high (43.1%) when compared to the Western countries (10-20%). TAL-1 deletion is the most common genetic...
7.
Parija T, Shirley S, Uma S, Rajalekshmy K, Ayyappan S, Rajkumar T
J Biosci . 2005 Jul; 30(3):371-6. PMID: 16052075
The Ewing's sarcoma family can present diagnostic difficulties. In the past the basis of diagnosis has been a exclusion. Identification of a specific translocation especially t(11;22) (EWS-FLI 1 fusion gene),...
8.
Chandra A, Sagar T, Raman S, Rajalekshmy K
Indian J Chest Dis Allied Sci . 2002 Feb; 44(1):53-5. PMID: 11845934
A case of primary mediastinal extragonadal germ cell tumour with involvement of bone marrow, a rare finding, is reported with a review of literature.
9.
Nirmala K, Rajalekshmy K, Raman S, Shanta V, Rajkumar T
Leuk Res . 2002 Feb; 26(4):335-43. PMID: 11839375
Detection of MRD remains one of the major goals in the treatment of acute lymphoblastic leukemia (ALL). We have used the polymerase chain reaction (PCR)-heteroduplex (HD) analysis to assess and...
10.
Rajalekshmy K, Abitha A, Pramila R, Gnanasagar T, Shanta V
Leuk Res . 1997 Feb; 21(2):119-24. PMID: 9112428
Immunophenotypic analysis of 285 newly diagnosed previously untreated, unselected, acute lymphoblastic leukaemia cases carried out at the Cancer Institute (W.I.A) in Madras reveals that 126 (44.2%) cases showed T-immunophenotype. The...