K R Holme
Overview
Explore the profile of K R Holme including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
12
Citations
104
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
TYRRELL D, Horne A, Holme K, Preuss J, Page C
Adv Pharmacol
. 1999 May;
46:151-208.
PMID: 10332503
In this chapter we have described anti-inflammatory functions of heparin distinct from its traditional anticoagulant activity. We have presented in vivo data showing heparin's beneficial effects in various preclinical models...
2.
Holme K, PERLIN A
Carbohydr Res
. 1997 Jul;
302(1-2):7-12.
PMID: 9249948
Chitosans having degrees of acetylation (da) of 0.04, 0.10, and 0.22, respectively, were N-sulfated under a variety of reaction conditions. The derivatives obtained ranged in degree of sulfation (ds) from...
3.
Wang P, Ba Z, Reich S, Zhou M, Holme K, Chaudry I
Am J Physiol
. 1996 Apr;
270(4 Pt 2):H1294-302.
PMID: 8967369
Although heparinization of animals before hemorrhage improves cell and organ function, the potent anticoagulant activity of conventional heparin sodium precludes its potential clinical use. To determine whether a novel nonanticoagulant...
4.
Foxall C, Holme K, Liang W, Wei Z
Anal Biochem
. 1995 Nov;
231(2):366-73.
PMID: 8594987
Basic fibroblast growth factor (bFGF) is a member of the heparin-binding growth factor family that interacts with cell surface heparan sulfate (HS) proteoglycans and extracellular matrix heparin. Here we report...
5.
Zellweger R, Ayala A, Zhu X, Holme K, DeMaso C, Chaudry I
J Surg Res
. 1995 Jul;
59(1):211-8.
PMID: 7630130
Recent studies have shown that heparinization of animals prior to or even after hemorrhagic shock improves tissue perfusion and organ function. However, the anticoagulant properties of conventional heparin preclude its...
6.
Rej R, Holme K, PERLIN A
Carbohydr Res
. 1990 Oct;
207(2):143-52.
PMID: 2076515
Heparin forms a complex with cupric ion (Cu2+) at a level of less than or equal to 10(-3) mol of the metal ion per dimeric unit of the polymer, as...
7.
Neville G, Mori F, Racey T, Rochon P, Holme K, PERLIN A
J Pharm Sci
. 1990 Apr;
79(4):339-43.
PMID: 2161921
Several low molecular weight (LMW) heparin sodium derivatives from different sources, as well as some related regular heparin sodium preparations, were examined for chemical composition by high field (300 MHz)...
8.
Dietrich C, Nader H, de Paiva J, Santos E, Holme K, PERLIN A
Int J Biol Macromol
. 1989 Dec;
11(6):361-6.
PMID: 2489105
The structural features and anticoagulant activity of heparins isolated from three species of molluscs (Anomalocardia brasiliana, Donnax striatus and Tivela mactroides) are reported. It is shown by chemical analyse, type...
9.
Holme K, PERLIN A
Carbohydr Res
. 1989 Mar;
186(2):301-12.
PMID: 2500236
Characteristics of the 1H-n.m.r. spectra of heparin admixed with other glycosaminoglycans are described with respect to the identification of the latter as possible contaminants of pharmaceutical heparins. Chemical shift differences...
10.
Neville G, Mori F, Holme K, PERLIN A
J Pharm Sci
. 1989 Feb;
78(2):101-4.
PMID: 2541240
High-field (300 MHz) 1H NMR spectral analyses are reported for various sodium or calcium heparin products available on the Canadian market. Dermatan sulfate (chondroitin sulfate B) was detected as a...