K Podsypanina
Overview
Explore the profile of K Podsypanina including associated specialties, affiliations and a list of published articles.
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8
Citations
2556
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0
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Recent Articles
1.
Johnston A, Bu W, Hein S, Garcia S, Camacho L, Xue L, et al.
Breast Cancer Res
. 2018 May;
20(1):42.
PMID: 29778097
Background: Psychiatric medications are widely prescribed in the USA. Many antipsychotics cause serum hyperprolactinemia as an adverse side effect; prolactin-Janus kinase 2 (JAK2)-signal transducer and activator of transcription 5 (STAT5)...
2.
Varmus H, Pao W, Politi K, Podsypanina K, Du Y
Cold Spring Harb Symp Quant Biol
. 2006 Jul;
70:1-9.
PMID: 16869733
Mutations of proto-oncogenes are common events in the pathogenesis of cancers, as shown in a wide range of studies during the 30 years since the discovery of these genes. The...
3.
Kwabi-Addo B, Giri D, Schmidt K, Podsypanina K, Parsons R, Greenberg N, et al.
Proc Natl Acad Sci U S A
. 2001 Sep;
98(20):11563-8.
PMID: 11553783
The PTEN gene encodes a lipid phosphatase that negatively regulates the phosphatidylinositol 3-kinase pathway and is inactivated in a wide variety of malignant neoplasms. High rates of loss of heterozygosity...
4.
Podsypanina K, Lee R, Politis C, Hennessy I, Crane A, Puc J, et al.
Proc Natl Acad Sci U S A
. 2001 Aug;
98(18):10320-5.
PMID: 11504907
PTEN phosphatase acts as a tumor suppressor by negatively regulating the phosphoinositide 3-kinase (PI3K) signaling pathway. It is unclear which downstream components of this pathway are necessary for oncogenic transformation....
5.
Li Y, Podsypanina K, Liu X, Crane A, Tan L, Parsons R, et al.
BMC Mol Biol
. 2001 Feb;
2:2.
PMID: 11178110
Background: Germline mutations in the tumor suppressor PTEN predispose human beings to breast cancer, and genetic and epigenetic alterations of PTEN are also detected in sporadic human breast cancer. Germline...
6.
Podsypanina K, Ellenson L, Nemes A, Gu J, Tamura M, Yamada K, et al.
Proc Natl Acad Sci U S A
. 1999 Feb;
96(4):1563-8.
PMID: 9990064
Pten/Mmac1+/- heterozygous mice exhibited neoplasms in multiple organs including the endometrium, liver, prostate, gastrointestinal tract, thyroid, and thymus. Loss of the wild-type allele was detected in neoplasms of the thymus...
7.
Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang S, et al.
Science
. 1997 Mar;
275(5308):1943-7.
PMID: 9072974
Mapping of homozygous deletions on human chromosome 10q23 has led to the isolation of a candidate tumor suppressor gene, PTEN, that appears to be mutated at considerable frequency in human...
8.
Mayford M, Baranes D, Podsypanina K, Kandel E
Proc Natl Acad Sci U S A
. 1996 Nov;
93(23):13250-5.
PMID: 8917577
Neuronal signaling requires that synaptic proteins be appropriately localized within the cell and regulated there. In mammalian neurons, polyribosomes are found not just in the cell body, but also in...