K P Nugent
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Explore the profile of K P Nugent including associated specialties, affiliations and a list of published articles.
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30
Citations
543
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Recent Articles
11.
Nugent K, Spigelman A, Phillips R
Dis Colon Rectum
. 1996 Jun;
39(6):659-62.
PMID: 8646953
Background: Recent work has demonstrated a correlation between frequency of aspirin ingestion and colorectal cancer prevention. Sulindac, another nonsteroidal anti-inflammatory drug (NSAID), has been shown to cause polyp regression and...
12.
Nugent K
Ann R Coll Surg Engl
. 1995 Sep;
77(5):372-6.
PMID: 7486766
Attempts at improving outcome from colorectal cancer have recently focused on prevention. This paper describes how both surgical and chemotherapeutic intervention can cause a fall in cell proliferation, polyp regression...
13.
Debinski H, Trojan J, Nugent K, Spigelman A, Phillips R
Lancet
. 1995 Apr;
345(8953):855-6.
PMID: 7898240
No abstract available.
14.
Spigelman A, Farmer K, Oliver S, Nugent K, Bennett P, Notarianni L, et al.
Gut
. 1995 Feb;
36(2):251-4.
PMID: 7883225
Patients with familial adenomatous polyposis (FAP) and age and sex matched controls were tested for cytochrome P4501A2 (CYP1A2), N-acetyltransferase, and xanthine oxidase activities using caffeine urinary metabolites as a discriminator....
15.
Thomas M, Nugent K, Forbes A, Williamson R
Gut
. 1994 Dec;
35(12):1718-20.
PMID: 7829008
Vitamin D3 reduces human rectal crypt cell production rate (CCPR) and may thereby protect against colorectal cancer. Cell turnover is increased in ulcerative proctocolitis, which might therefore respond to vitamin...
16.
Nugent K, Spigelman A, Williams C, Talbot I, Phillips R
J R Soc Med
. 1994 Nov;
87(11):704-6.
PMID: 7837198
Familial adenomatous polyposis (FAP) is characterized by the presence of premalignant adenomas of the large and small bowel. Prophylactic colectomy deals with the risk for colon cancer, leaving duodenal cancer...
17.
Nugent K, Phillips R, Hodgson S, Cottrell S, Smith-Ravin J, Pack K, et al.
Gut
. 1994 Nov;
35(11):1622-3.
PMID: 7828985
The phenotypic expression in familial adenomatous polyposis (FAP) is variable. This study compares the phenotype of 27 patients with an identical 5 base pair (bp) deletion at codon 1309 with...
18.
Spigelman A, Talbot I, Penna C, Nugent K, Phillips R, Costello C, et al.
J Clin Pathol
. 1994 Aug;
47(8):709-10.
PMID: 7962621
Aims: To explore the association between duodenal adenoma and carcinoma in patients with familial adenomatous polyposis (FAP). Methods: A multicentre survey of 1262 patients with FAP yielded 47 cases of...
19.
Nugent K, Spigelman A, Talbot I, Phillips R
Br J Surg
. 1994 Feb;
81(2):291-2.
PMID: 8156364
No abstract available.
20.
Spigelman A, Nugent K, Penna C, Foulds S, Phillips R
Cancer Detect Prev
. 1994 Jan;
18(4):253-8.
PMID: 7982235
Patients with familial adenomatous polyposis (FAP) are at high risk for duodenal tumors, the distribution of which suggests that bile is important in their development. Studies of the bile of...