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K P Nephew

Explore the profile of K P Nephew including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 850
Followers 0
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Recent Articles
1.
Anjanappa M, Hao Y, Simpson E, Bhat-Nakshatri P, Nelson J, Tersey S, et al.
Oncogene . 2017 Sep; 37(2):185-196. PMID: 28892047
Tumor complexity and intratumor heterogeneity contribute to subclonal diversity. Despite advances in next-generation sequencing (NGS) and bioinformatics, detecting rare mutations in primary tumors and metastases contributing to subclonal diversity is...
2.
Ozes A, Miller D, Ozes O, Fang F, Liu Y, Matei D, et al.
Oncogene . 2016 Apr; 35(41):5350-5361. PMID: 27041570
The transcription factor nuclear factor kappa B (NF-κB) and the long non-coding RNA (lncRNA) HOTAIR (HOX transcript antisense RNA) have diverse functional roles in cancer. In this study, we show...
3.
Rhodes L, Tate C, Hoang V, Burks H, Gilliam D, Martin E, et al.
Oncogenesis . 2015 Oct; 4:e168. PMID: 26436950
Liver kinase B1 (LKB1), also known as serine/threonine kinase 11 (STK11), has been identified as a tumor suppressor in many cancers including breast. Low LKB1 expression has been associated with...
4.
Lengyel E, Burdette J, Kenny H, Matei D, Pilrose J, Haluska P, et al.
Oncogene . 2013 Aug; 33(28):3619-33. PMID: 23934194
Epithelial ovarian cancer (OvCa) is associated with high mortality and, as the majority (>75%) of women with OvCa have metastatic disease at the time of diagnosis, rates of survival have...
5.
Rao X, Evans J, Chae H, Pilrose J, Kim S, Yan P, et al.
Oncogene . 2012 Nov; 32(38):4519-28. PMID: 23128390
Caveolin-1 (Cav1) is an integral membrane, scaffolding protein found in plasma membrane invaginations (caveolae). Cav1 regulates multiple cancer-associated processes. In breast cancer, a tumor suppressive role for Cav1 has been...
6.
Rao X, Di Leva G, Li M, Fang F, Devlin C, Hartman-Frey C, et al.
Oncogene . 2010 Nov; 30(9):1082-97. PMID: 21057537
Fulvestrant is a selective estrogen receptor downregulator (SERD) and highly effective antagonist to hormone-sensitive breast cancers following failure of previous tamoxifen or aromatase inhibitor therapies. However, after prolonged fulvestrant therapy,...
7.
Abbosh P, Li X, Li L, Gardner T, Kao C, Nephew K
Cancer Gene Ther . 2007 Jan; 14(4):399-408. PMID: 17218945
Thyroid cancer affects between 10,000 and 15,000 people per year in the US. Typically, this disease can be controlled with surgical resection and radioiodide treatment. However, resistance to these conventional...
8.
Ahluwalia A, Hurteau J, Bigsby R, Nephew K
Gynecol Oncol . 2001 Sep; 82(2):299-304. PMID: 11531283
Objective: The aim of this study was to investigate whether expression of the enzymes that catalyze cytosine CpG island methylation, DNA methyltransferases, DNMT1, DNMT3a, and DNMT3b is altered in human...
9.
Ahluwalia A, Yan P, Hurteau J, Bigsby R, Jung S, Huang T, et al.
Gynecol Oncol . 2001 Sep; 82(2):261-8. PMID: 11531277
Objective: The aim of this study was to examine CpG island methylation patterns in ovarian cancer and determine whether epigenetic information can be related to clinical data of patients. CpG...
10.
Cardenas H, Burke K, Bigsby R, Pope W, Nephew K
Biol Reprod . 2001 Jun; 65(1):128-34. PMID: 11420232
Objectives were to sequence and examine the expression of the estrogen receptor beta (ERbeta) in the sheep ovary. The sequence of the ovine ERbeta (oERbeta) was determined using reverse-transcription polymerase...