K Negoro
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Explore the profile of K Negoro including associated specialties, affiliations and a list of published articles.
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Articles
55
Citations
370
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Recent Articles
1.
Kakuta Y, Naito T, Onodera M, Kuroha M, Kimura T, Shiga H, et al.
Pharmacogenomics J
. 2015 Jun;
16(3):280-5.
PMID: 26076924
The efficacy of thiopurines, including azathioprine (AZA) and 6-mercaptopurine (6MP), has been demonstrated for the treatment of inflammatory bowel disease (IBD). The most common and serious adverse event of treatment...
2.
Aizawa H, Kinouchi Y, Negoro K, Nomura E, Imai G, Takahashi S, et al.
Tissue Antigens
. 2009 Jun;
73(6):569-74.
PMID: 19493234
Recently, a genome-wide association study for ulcerative colitis (UC) in the UK population was reported, and several susceptibility loci including the human leukocyte antigen (HLA) region were identified. The strongest...
3.
Negoro K, Kobayashi S, Takeno K, Uchida K, Baba H
Clin Exp Rheumatol
. 2008 Sep;
26(4):534-41.
PMID: 18799081
Objectives: This study examined how physiological levels of extracellular osmolarity influence proteoglycan accumulation in articular chondrocytes in a three-dimensional culture system. Methods: Cells were obtained from metacarpal phalangeal joints of...
4.
Matsumura Y, Kinouchi Y, Nomura E, Negoro K, Kakuta Y, Endo K, et al.
Tissue Antigens
. 2008 Apr;
71(5):447-52.
PMID: 18416774
The human leukocyte antigen (HLA) region has been implicated in the disease susceptibility of inflammatory bowel disease by several linkage and association studies. In Caucasians, HLA-DRB1 has been reported to...
5.
Mochida A, Kinouchi Y, Negoro K, Takahashi S, Takagi S, Nomura E, et al.
Tissue Antigens
. 2007 Jul;
70(2):128-35.
PMID: 17610417
The human leukocyte antigen (HLA) region has been implicated in the pathogenesis of inflammatory bowel disease (IBD), which is classified into Crohn's disease (CD) and ulcerative colitis (UC). Recently, an...
6.
Kakuta Y, Kinouchi Y, Negoro K, Takahashi S, Shimosegawa T
Gut
. 2006 Sep;
55(10):1527-8.
PMID: 16966713
No abstract available.
7.
Oomori S, Takagi S, Kikuchi T, Utsunomiya K, Yokoyama H, Negoro K, et al.
Endoscopy
. 2005 Apr;
37(4):346-50.
PMID: 15824945
Background And Study Aims: Patients with intestinal graft-versus-host disease (GVHD) are generally in poor clinical condition. In this study we aimed to establish the clinical significance of endoscopic diagnosis of...
8.
Nomura E, Kinouchi Y, Negoro K, Kojima Y, Oomori S, Sugimura M, et al.
Genes Immun
. 2004 Jun;
5(6):477-83.
PMID: 15215890
Ulcerative colitis (UC) is a multifactorial disorder with both genetic and environmental factors. HLA-B*52 and DRB1*1502 are reported to be strongly associated with UC in Japan. However, the actual susceptible...
9.
Takahashi K, Satoh J, Kojima Y, Negoro K, Hirai M, Hinokio Y, et al.
Tissue Antigens
. 2004 Mar;
63(3):231-6.
PMID: 14989712
Defective function of antigen-presenting cells has been postulated to be one of the non-HLA-linked susceptibility factors for type 1 diabetes mellitus, though the underlying genetic factors remain unclear. SLC11A1 (formerly...
10.
Negoro K, McGovern D, Kinouchi Y, Takahashi S, Lench N, Shimosegawa T, et al.
Gut
. 2003 Mar;
52(4):541-6.
PMID: 12631666
Background And Aims: Genetic variation in the chromosome 5q31 cytokine cluster (IBD5 risk haplotype) has been associated with Crohn's disease (CD) in a Canadian population. We studied the IBD5 risk...