K Monkhorst
Overview
Explore the profile of K Monkhorst including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
18
Citations
192
Followers
0
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Recent Articles
11.
van Veggel B, Madeira R Santos J, Hashemi S, Paats M, Monkhorst K, Heideman D, et al.
Lung Cancer
. 2020 Jan;
141:9-13.
PMID: 31926441
Objectives: Epidermal growth factor receptor (EGFR) exon 20 insertions comprise 4-10 % of EGFR mutations in non-small cell lung cancer (NSCLC) and are associated with primary resistance to first and...
12.
Thunnissen E, Lissenberg-Witte B, van den Heuvel M, Monkhorst K, Skov B, Sorensen J, et al.
Lung Cancer
. 2019 Oct;
138:13-18.
PMID: 31630043
Objective: Metastasized non-small cell lung cancer (NSCLC) with an anaplastic lymphoma kinase (ALK) rearrangement is usually sensitive to a range of ALK-tyrosine kinase inhibitors. ALK-positive NSCLC have been identified in...
13.
de Vries R, Muller M, van der Noort V, Theelen W, Schouten R, Hummelink K, et al.
Ann Oncol
. 2019 Sep;
30(10):1660-1666.
PMID: 31529107
Background: Immune checkpoint inhibitors have improved survival outcome of advanced non-small-cell lung cancer (NSCLC). However, most patients do not benefit. Therefore, biomarkers are needed that accurately predict response. We hypothesized...
14.
Kerr K, Dafni U, Schulze K, Thunnissen E, Bubendorf L, Hager H, et al.
Ann Oncol
. 2017 Nov;
29(1):200-208.
PMID: 29186353
Background: Reported prevalence of driver gene mutations in non-small-cell lung cancer (NSCLC) is highly variable and clinical correlations are emerging. Using NSCLC biomaterial and clinical data from the European Thoracic...
15.
Ditzel M, Deerenberg E, Grotenhuis N, Harlaar J, Monkhorst K, Bastiaansen-Jenniskens Y, et al.
Surg Endosc
. 2013 Apr;
27(10):3654-62.
PMID: 23549771
Background: In laparoscopic incisional hernia repair, direct contact between the prosthesis and the abdominal viscera is inevitable, which may lead to an inflammatory reaction resulting in abdominal adhesion formation. This...
16.
Daams F, Monkhorst K, van den Broek J, Slieker J, Jeekel J, Lange J
Eur Surg Res
. 2013 Apr;
50(1):24-31.
PMID: 23548268
The role of local ischaemia in the pathogenesis of colorectal anastomotic leakage (AL) is not known. This study investigates the role of local ischaemia caused by sutures in an experimental...
17.
Mitalas L, van Onkelen R, Monkhorst K, Zimmerman D, Gosselink M, Schouten W
Tech Coloproctol
. 2012 Jan;
16(2):113-7.
PMID: 22231563
Background: At present, transanal advancement flap repair (TAFR) is the treatment of choice for transsphincteric fistulas passing through the upper and middle third of the external anal sphincter. It has...
18.
McMorrow T, van den Wijngaard A, Wollenschlaeger A, van de Corput M, Monkhorst K, Trimborn T, et al.
EMBO J
. 2000 Sep;
19(18):4986-96.
PMID: 10990462
Locus control regions (LCRs) alleviate chromatin-mediated transcriptional repression. Incomplete LCRs partially lose this property when integrated in transcriptionally restrictive genomic regions such as centromeres. This frequently results in position effect...