K M Wilcox
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Explore the profile of K M Wilcox including associated specialties, affiliations and a list of published articles.
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9
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156
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Recent Articles
1.
Wilcox K, Lindsey K, Votaw J, Goodman M, Martarello L, Carroll F, et al.
Synapse
. 2001 Dec;
43(1):78-85.
PMID: 11746736
Dopaminergic mechanisms are thought to play a central role in the reinforcing effects of cocaine. The present study examined the reinforcing effects of 3beta-(4-chlorophenyl)tropane-2beta-carboxylic acid phenyl ester (RTI-113), a long-acting,...
2.
Wilcox K, Paul I, Ordway G, Woolverton W
Psychopharmacology (Berl)
. 2001 Oct;
157(3):260-8.
PMID: 11605081
Rationale: Local anesthetics bind to the dopamine transporter (DAT), inhibit dopamine (DA) uptake and have been reported to have cocaine-like discriminative stimulus effects. The hypothesis of the present study was...
3.
Howell L, Wilcox K
J Pharmacol Exp Ther
. 2001 Jun;
298(1):1-6.
PMID: 11408518
Despite intensive medication development efforts, no effective pharmacotherapy for cocaine abuse has demonstrated efficacy for long-term use. Given the obvious importance of the dopamine transporter in the addictive properties of...
4.
Wilcox K, Rowlett J, Paul I, Ordway G, Woolverton W
Psychopharmacology (Berl)
. 2001 Mar;
153(1):139-47.
PMID: 11255924
Rationale: Drugs that are self-administered appear to vary in their potency and effectiveness as positive reinforcers. Understanding mechanisms that determine relative effectiveness of drugs as reinforcers will enhance our understanding...
5.
Woolverton W, Rowlett J, Wilcox K, Paul I, Kline R, Newman A, et al.
Psychopharmacology (Berl)
. 2000 Feb;
147(4):426-35.
PMID: 10672637
Rationale: The reinforcing effects of many psychomotor stimulants have been related to increased dopaminergic neurotransmission. Drugs that block dopamine (DA) uptake have generally been found to function as positive reinforcers....
6.
Rowlett J, Wilcox K, Woolverton W
Psychopharmacology (Berl)
. 1999 Sep;
145(3):324-32.
PMID: 10494582
Rationale And Objectives: The role of benzodiazepine (BZ) receptor mechanisms in modulating the stimulus effects of the BZ partial inverse agonist ethyl-beta-carboline-3-carboxylate (beta-CCE) are not well understood. The purpose of...
7.
Wilcox K, Paul I, Woolverton W
Eur J Pharmacol
. 1999 Mar;
367(2-3):175-81.
PMID: 10078990
Local anesthetics bind to dopamine transporters and inhibit dopamine uptake in rodent brain. Additionally, local anesthetics are self-administered in rhesus monkeys. The present study determined binding affinities of cocaine and...
8.
Rowlett J, Wilcox K, Woolverton W
J Pharmacol Exp Ther
. 1998 Jul;
286(1):61-9.
PMID: 9655842
Low, nonreinforcing doses of heroin have been shown to shift the dose-response function of cocaine leftward in rhesus monkeys trained under a progressive-ratio schedule of i.v. drug injection. Our study...
9.
Kantak K, Edwards M, Wilcox K, Kitchel E
J Pharmacol Exp Ther
. 1997 Oct;
283(1):200-6.
PMID: 9336325
Previous studies suggest that magnesium chloride may have discriminative stimulus effects that partially overlap with those of noncompetitive N-methyl-D-aspartate antagonists as well as certain monoamine uptake inhibitors. In our study,...