K L Lorick
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Explore the profile of K L Lorick including associated specialties, affiliations and a list of published articles.
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4
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483
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Recent Articles
1.
Brauweiler A, Lorick K, Lee J, Tsai Y, Chan D, Weissman A, et al.
Oncogene
. 2006 Oct;
26(16):2263-71.
PMID: 17016439
TRC8/RNF139 and von Hippel-Lindau (VHL) both encode E3 ubiquitin (Ub) ligases mutated in clear-cell renal carcinomas (ccRCC). VHL, inactivated in nearly 70% of ccRCCs, is a tumor suppressor encoding the...
2.
Hakli M, Lorick K, Weissman A, Janne O, Palvimo J
FEBS Lett
. 2004 Feb;
560(1-3):56-62.
PMID: 14987998
SNURF/RNF4 has been implicated in transcriptional regulation and growth inhibition in a RING finger-dependent fashion. In this work, we show that SNURF mediates its own ubiquitination in vitro in a...
3.
Lorick K, Jensen J, Fang S, Ong A, Hatakeyama S, Weissman A
Proc Natl Acad Sci U S A
. 1999 Sep;
96(20):11364-9.
PMID: 10500182
A RING finger-containing protein (AO7) that binds ubiquitin-conjugating enzymes (E2s) and is a substrate for E2-dependent ubiquitination was identified. Mutations of cation-coordinating residues within AO7's RING finger abolished ubiquitination, as...
4.
Lorick K, Toscano D, Toscano Jr W
Biochem Biophys Res Commun
. 1998 Mar;
243(3):749-52.
PMID: 9501000
Actions of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on all-trans-retinoic acid (trans-RA) binding to retinoic acid receptors (RARs) in cultured human keratinocytes (SCC-12F) was investigated. TCDD and trans-RA elicited opposing actions on the production...