Alpha 2.0
Login Register
» Authors » K L Kotloff

K L Kotloff

Explore the profile of K L Kotloff including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 44
Citations 1317
Followers 0
Related Specialties
Allergy & Immunology
Pediatrics
Infectious Diseases
Top 10 Co-Authors
M M Levine
S S Wasserman
G A Losonsky
J P Nataro
J G Morris Jr
M B Sztein
R Edelman
J D Clemens
C O Tacket
J C Sadoff
Published In
Infect Immun
Pediatr Infect Dis J
Vaccine
J Infect Dis
J Clin Microbiol
Affiliations
Soon will be listed here.
Recent Articles
1.
Factors associated with typical enteropathogenic infection among children <5 years old with moderate-to-severe diarrhoea in rural western Kenya, 2008-2012
Fagerli K, Omore R, Kim S, Ochieng J, Ayers T, Juma J, et al.
Epidemiol Infect . 2020 Nov; 148:e281. PMID: 33190663
Typical enteropathogenic Escherichia coli (tEPEC) infection is a major cause of diarrhoea and contributor to mortality in children <5 years old in developing countries. Data were analysed from the Global...
2.
Diarrhoea, enteric pathogen detection and nutritional indicators among controls in the Global Enteric Multicenter Study, Kenya site: an opportunity to understand reference populations in case-control studies of diarrhoea
Berendes D, OReilly C, Kim S, Omore R, Ochieng J, Ayers T, et al.
Epidemiol Infect . 2018 Nov; 147:e44. PMID: 30428944
Given the challenges in accurately identifying unexposed controls in case-control studies of diarrhoea, we examined diarrhoea incidence, subclinical enteric infections and growth stunting within a reference population in the Global...
3.
Antigen-specific IgA B memory cell responses to Shigella antigens elicited in volunteers immunized with live attenuated Shigella flexneri 2a oral vaccine candidates
Simon J, Maciel Jr M, Weld E, Wahid R, Pasetti M, Picking W, et al.
Clin Immunol . 2011 Mar; 139(2):185-92. PMID: 21388888
We studied the induction of antigen-specific IgA memory B cells (B(M)) in volunteers who received live attenuated Shigella flexneri 2a vaccines. Subjects ingested a single oral dose of 10(7), 10(8)...
4.
Antigen-specific B memory cell responses to lipopolysaccharide (LPS) and invasion plasmid antigen (Ipa) B elicited in volunteers vaccinated with live-attenuated Shigella flexneri 2a vaccine candidates
Simon J, Wahid R, Maciel Jr M, Picking W, Kotloff K, Levine M, et al.
Vaccine . 2008 Nov; 27(4):565-72. PMID: 19022324
We evaluated B memory responses in healthy adult volunteers who received one oral dose of live-attenuated Shigella flexneri 2a vaccine. LPS-specific B(M) cells increased from a median of 0 at...
5.
Genotypic analysis of invasive Streptococcus pneumoniae from Mali, Africa, by semiautomated repetitive-element PCR and pulsed-field gel electrophoresis
Harrington S, Stock F, Kominski A, Campbell J, Hormazabal J, Livio S, et al.
J Clin Microbiol . 2006 Dec; 45(3):707-14. PMID: 17192418
As part of a large, ongoing study of invasive infections in pediatric patients in Bamako, Mali, 106 cases of invasive pneumococcal disease were identified from June 2002 to July 2003...
6.
Safety and immunogenicity of oral inactivated whole-cell Helicobacter pylori vaccine with adjuvant among volunteers with or without subclinical infection
Kotloff K, Sztein M, Wasserman S, Losonsky G, DiLorenzo S, Walker R
Infect Immun . 2001 May; 69(6):3581-90. PMID: 11349017
Helicobacter pylori infection of the gastric mucosa can be found in approximately 50% of the world's population and is associated with a range of pathology, including peptic ulcer, atrophic gastritis,...
7.
Safety and immunogenicity of increasing doses of a Clostridium difficile toxoid vaccine administered to healthy adults
Kotloff K, Wasserman S, Losonsky G, THOMAS Jr W, Nichols R, Edelman R, et al.
Infect Immun . 2001 Feb; 69(2):988-95. PMID: 11159994
Clostridium difficile is a major cause of nosocomial diarrhea in industrialized countries. Although most illnesses respond to available therapy, infection can increase morbidity, prolong hospitalization, and produce life-threatening colitis. Vaccines...
8.
Phase 2 clinical trial of attenuated Salmonella enterica serovar typhi oral live vector vaccine CVD 908-htrA in U.S. volunteers
Tacket C, Sztein M, Wasserman S, Losonsky G, Kotloff K, Wyant T, et al.
Infect Immun . 2000 Feb; 68(3):1196-201. PMID: 10678926
Salmonella enterica serovar Typhi strain CVD 908-htrA is a live attenuated strain which may be useful as an improved oral typhoid vaccine and as a vector for cloned genes of...
9.
Shigella flexneri 2a strain CVD 1207, with specific deletions in virG, sen, set, and guaBA, is highly attenuated in humans
Kotloff K, Noriega F, Samandari T, Sztein M, Losonsky G, Nataro J, et al.
Infect Immun . 2000 Feb; 68(3):1034-9. PMID: 10678904
A phase 1 clinical trial was conducted among 35 healthy adult volunteers to evaluate the safety, immunogenicity, and shedding of different doses of CVD 1207, a live attenuated Shigella flexneri...
10.
Production of IFN-gamma and IL-10 to Shigella invasins by mononuclear cells from volunteers orally inoculated with a Shiga toxin-deleted Shigella dysenteriae type 1 strain
Samandari T, Kotloff K, Losonsky G, Picking W, Sansonetti P, Levine M, et al.
J Immunol . 2000 Feb; 164(4):2221-32. PMID: 10657678
Volunteers were orally administered invasive, non-Shiga toxin-producing Shigella dysenteriae 1 to establish a challenge model to assess vaccine efficacy. In stepwise fashion, four separate groups were given 3 x 10(2),...