K J Neelis
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Explore the profile of K J Neelis including associated specialties, affiliations and a list of published articles.
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22
Citations
241
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Recent Articles
11.
Wagemaker G, Neelis K, Hartong SCC , Wognum A, Thomas G, Fielder P, et al.
Stem Cells
. 2000 Sep;
16 Suppl 2:127-41.
PMID: 11012185
Radiation-induced pancytopenia proved to be a suitable model system in mice and rhesus monkeys to study thrombopoietin (TPO) target cell range and efficacy. TPO was highly effective in rhesus monkeys...
12.
Wagemaker G, Hartong S, Neelis K, Egeland T, Wognum A
Stem Cells
. 2000 Sep;
16 Suppl 1:185-91.
PMID: 11012161
Under conditions of steady-state hemopoiesis, a small fraction of immature hemopoietic cells, including stem cells, circulates in peripheral blood (PB). In rhesus monkeys, a median number of 1.2 x 10(7)/l...
13.
Hartong S, Neelis K, Visser T, Wagemaker G
Exp Hematol
. 2000 Jul;
28(7):753-9.
PMID: 10907636
Objective: If administered in a sufficiently high dose to overcome receptor-mediated clearance and in a well-scheduled manner, thrombopoietin (TPO) prominently stimulates hematopoietic reconstitution following myelosuppressive treatment and potentiates the efficacy...
14.
Griffiths N, Linard C, Dublineau I, Francois A, Esposito V, Neelis K, et al.
Int J Radiat Biol
. 1999 Mar;
75(2):183-91.
PMID: 10072179
Purpose: To investigate the long-term effects of X-irradiation on different aspects of gastrointestinal function in the non-human primate (Macaca mulatta). Materials And Methods: Animals were exposed to X-radiation (5 or...
15.
Wagemaker G, Neelis K, Hartong S, Wognum A, Thomas G, Fielder P, et al.
Stem Cells
. 1998 Dec;
16(6):375-86.
PMID: 9831863
Radiation-induced pancytopenia proved to be a suitable model system in mice and rhesus monkeys for studying thrombopoietin (TPO) target cell range and efficacy. TPO was highly effective in rhesus monkeys...
16.
Neelis K, Visser T, Dimjati W, Thomas G, Fielder P, Bloedow D, et al.
Blood
. 1998 Aug;
92(5):1586-97.
PMID: 9716586
Thrombopoietin (TPO) has been used in preclinical myelosuppression models to evaluate the effect on hematopoietic reconstitution. Here we report the importance of dose and dose scheduling for multilineage reconstitution after...
17.
Neelis K, Hartong S, Egeland T, Thomas G, Eaton D, Wagemaker G
Blood
. 1997 Nov;
90(7):2565-73.
PMID: 9326222
Thrombopoietin (TPO) was evaluated for efficacy in a placebo-controlled study in rhesus monkeys with concurrent administration of either granulocyte/macrophage colony-stimulating factor (GM-CSF) or granulocyte CSF, (G-CSF). Rhesus monkeys were subjected...
18.
Neelis K, Dubbelman Y, Wognum A, Thomas G, Eaton D, Egeland T, et al.
Exp Hematol
. 1997 Sep;
25(10):1094-103.
PMID: 9293907
The efficacy of recombinant human thrombopoietin (TPO) and recombinant human granulocyte colony stimulating factor (G-CSF) in stimulating platelet and neutrophil recovery was evaluated in a placebo-controlled study involving transplantation of...
19.
Neelis K, Dubbelman Y, Qingliang L, Thomas G, Eaton D, Wagemaker G
Exp Hematol
. 1997 Sep;
25(10):1084-93.
PMID: 9293906
Simultaneous treatment with human thrombopoietin (TPO) and granulocyte colony-stimulating factor (G-CSF) was evaluated in a placebo-controlled rhesus monkey study using 5 Gy total body irradiation (TBI) to induce 3 weeks...
20.
Neelis K, Qingliang L, Thomas G, Cohen B, Eaton D, Wagemaker G
Blood
. 1997 Jul;
90(1):58-63.
PMID: 9207438
The effectiveness of thrombopoietin (TPO) in alleviating thrombocytopenia was evaluated in a placebo-controlled study involving rhesus monkeys exposed to 5 Gy total-body irradiation (TBI) (300-kV x-rays) to result in 3...