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K Isaacs

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Articles 24
Citations 375
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Recent Articles
1.
Hirsch G, Trusheim M, Cobbs E, Bala M, Garner S, Hartman D, et al.
Clin Pharmacol Ther . 2017 Mar; 101(4):542. PMID: 28318021
No abstract available.
2.
Hirsch G, Trusheim M, Cobbs E, Bala M, Garner S, Hartman D, et al.
Clin Pharmacol Ther . 2016 Sep; 100(6):685-698. PMID: 27626610
The current system of biomedical innovation is unable to keep pace with scientific advancements. We propose to address this gap by reengineering innovation processes to accelerate reliable delivery of products...
3.
Goldsmith M, Grulke C, Brooks R, Transue T, Tan Y, Frame A, et al.
Food Chem Toxicol . 2013 Dec; 65:269-79. PMID: 24374094
Consumer products are a primary source of chemical exposures, yet little structured information is available on the chemical ingredients of these products and the concentrations at which ingredients are present....
4.
Bennett C, Lawson V, Brickell K, Isaacs K, Seltzer W, Lipe H, et al.
Neurology . 2008 May; 71(1):14-20. PMID: 18495953
Background: Hereditary motor-sensory neuropathy or the Charcot-Marie-Tooth syndrome is known to represent considerable genetic heterogeneity. Onset is usually in childhood, adolescence, or young adulthood. The objective of this study was...
5.
Isaacs K, Haim N
J Chemother . 2005 Jul; 17(3):339-42. PMID: 16038530
Capecitabine can interact with warfarin, resulting in altered coagulation parameters and bleeding. Four cases have been reported. We describe a fifth case with life-threatening interaction between these two drugs. A...
6.
Ryan E, Morgello S, Isaacs K, Naseer M, Gerits P
Neurology . 2004 Mar; 62(6):957-62. PMID: 15037699
Objective: To determine whether hepatitis C (HCV) contributes to CNS dysfunction among HIV-infected individuals. Methods: Using a cross-sectional design, the neuropsychiatric profile of individuals with advanced HIV coinfected with hepatitis...
7.
Schreiber S, Fedorak R, Nielsen O, Wild G, Williams C, Nikolaus S, et al.
Gastroenterology . 2000 Dec; 119(6):1461-72. PMID: 11113067
Background & Aims: Interleukin (IL)-10 is a cytokine with potent anti-inflammatory properties. We investigated the safety and efficacy of different doses of human recombinant (rhu)IL-10 in patients with Crohn's disease...
8.
Isaacs K, Brown G, Moore G
Exp Dermatol . 1998 Dec; 7(5):273-80. PMID: 9832315
Mutations of the X-linked genes Tabby (Ta) in mice and EDA in humans result in developmental and functional abnormalities, primarily in the skin and hair follicles. Although both genes are...
9.
Moore G, Jackson N, Isaacs K, Brown G
J Theor Biol . 1998 Jun; 191(1):87-94. PMID: 9593659
Models dealing with the development of hair and feather follicles commonly predict that the factors initiating morphogenesis also specify patterns of follicle distribution. The factors have been postulated as chemical...
10.
Shaheen N, Crosby M, Grimm I, Isaacs K
Gastrointest Endosc . 1998 Jan; 46(6):564-5. PMID: 9434231
No abstract available.