K I ORourke
Overview
Explore the profile of K I ORourke including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
833
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Recent Articles
1.
Cinar M, Schneider D, Waldron D, ORourke K, White S
Vet J
. 2018 Mar;
233:19-24.
PMID: 29486874
Scrapie is a transmissible spongiform encephalopathy of sheep and goats, and scrapie eradication programs in many parts of the world rely on strong genetic resistance to classical scrapie in sheep....
2.
Schneider D, Harrington R, Zhuang D, Yan H, Truscott T, Dassanayake R, et al.
J Comp Pathol
. 2012 May;
147(4):508-21.
PMID: 22595634
Transmissible spongiform encephalopathies (TSEs) are diagnosed by immunodetection of disease-associated prion protein (PrP(d)). The distribution of PrP(d) within the body varies with the time-course of infection and between species, during...
3.
Spraker T, ORourke K, Gidlewski T, Powers J, Greenlee J, Wild M
Vet Pathol
. 2010 Apr;
47(3):536-46.
PMID: 20382822
Eyes and nuclei of the visual pathways in the brain were examined in 30 Rocky Mountain elk (Cervus elaphus nelsoni) representing 3 genotypes of the prion protein gene PRNP (codon...
4.
Laegreid W, Clawson M, Heaton M, Green B, ORourke K, Knowles D
J Virol
. 2008 Jul;
82(20):10318-20.
PMID: 18632863
Variation in the ovine prion protein amino acid sequence influences scrapie progression, with sheep homozygous for A(136)R(154)Q(171) considered susceptible. This study examined the association of survival time of scrapie-exposed ARQ...
5.
Hamir A, Richt J, Miller J, Kunkle R, Hall S, Nicholson E, et al.
Vet Pathol
. 2008 May;
45(3):297-306.
PMID: 18487485
To compare clinical and pathologic findings of chronic wasting disease (CWD) in a natural host, 3 groups (n = 5) of white-tailed deer (WTD) fawns were intracerebrally inoculated with a...
6.
Evoniuk J, Johnson M, Borowicz P, Caton J, Vonnahme K, Reynolds L, et al.
Placenta
. 2008 Mar;
29(5):422-8.
PMID: 18358531
For placental transmission of scrapie to occur, the normal cellular prion protein (PrPC) must be converted to an abnormal infectious form known as PrPSc. PrPC genotype influences susceptibility to contracting...
7.
Baszler T, Kiupel M, Williams E, Thomsen B, Gidlewski T, Montgomery D, et al.
J Vet Diagn Invest
. 2006 Apr;
18(2):147-55.
PMID: 16617694
Two commercially available automated immunohistochemistry platforms, Ventana NexES and DakoCytomation Autostainer Universal Staining System, were compared for diagnosing sheep scrapie and cervid chronic wasting disease. Both automated platforms used the...
8.
Alexander B, Stobart R, Russell W, ORourke K, Lewis G, Logan J, et al.
J Anim Sci
. 2005 Jan;
83(2):455-9.
PMID: 15644519
Scrapie is one of several transmissible spongiform encephalopathies of livestock. Disease susceptibility is linked to polymorphisms in the normal prion protein gene that encodes the mammalian prion precursor. Codon 171...
9.
Spraker T, Balachandran A, Zhuang D, ORourke K
Vet Rec
. 2004 Oct;
155(10):295-302.
PMID: 15478500
Sections of medulla oblongata, taken at the level of the obex, palatine tonsil and medial retropharyngeal lymph node from 10,269 captive Rocky Mountain elk (Cervus elaphus nelsoni), were examined by...
10.
Bender S, Alverson J, Herrmann L, ORourke K
Vet Rec
. 2004 Jun;
154(21):662-3.
PMID: 15198315
No abstract available.