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K Hosiyama

Explore the profile of K Hosiyama including associated specialties, affiliations and a list of published articles. Areas
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1.
Izumi T, Hosiyama K, Enomoto S, Sasahara K, Sugiyama Y
J Pharmacol Exp Ther . 1997 Mar; 280(3):1392-400. PMID: 9067328
Sulfation and glucuronidation, the major routes of metabolism of troglitazone, an antidiabetic agent, were examined in vitro using hepatic cytosol and microsomes prepared from KK mice, an animal model of...
2.
Izumi T, Enomoto S, Hosiyama K, Sasahara K, Shibukawa A, Nakagawa T, et al.
J Pharmacol Exp Ther . 1996 Jun; 277(3):1630-41. PMID: 8667232
We have attempted to predict the human pharmacokinetics of troglitazone after oral administration based on animal data. Troglitazone is a new antidiabetic agent that exhibits a high-metabolic clearance and is...