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K Ejeskar

Explore the profile of K Ejeskar including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 9
Citations 130
Followers 0
Related Specialties
Oncology
Genetics
Pediatrics
Top 10 Co-Authors
T Martinsson
P Kogner
F Abel
R-M Sjoberg
H Caren
C Krona
S Fransson
R M Sjoberg
M K Andersson
A Uv
Published In
Br J Cancer
Med Pediatr Oncol
Int J Mol Med
Oncogene
Cytogenet Cell Genet
Affiliations
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Recent Articles
1.
p37δ is a new isoform of PI3K p110δ that increases cell proliferation and is overexpressed in tumors
Fransson S, Uv A, Eriksson H, Andersson M, Wettergren Y, Bergo M, et al.
Oncogene . 2011 Oct; 31(27):3277-86. PMID: 22020336
The phosphatidylinositol 3-kinases (PI3Ks) regulate cell growth, proliferation and survival, and are frequently affected in human cancer. PI3K is composed of a catalytic subunit, p110, and a regulatory subunit, p85....
2.
Genetic and epigenetic changes in the common 1p36 deletion in neuroblastoma tumours
Caren H, Fransson S, Ejeskar K, Kogner P, Martinsson T
Br J Cancer . 2007 Oct; 97(10):1416-24. PMID: 17940511
Chromosome 1p is frequently deleted in neuroblastoma (NB) tumours. The commonly deleted region has been narrowed down by loss of heterozygosity studies undertaken by different groups. Based on earlier mapping...
3.
A novel 1p36.2 located gene, APITD1, with tumour-suppressive properties and a putative p53-binding domain, shows low expression in neuroblastoma tumours
Krona C, Ejeskar K, Caren H, Abel F, Sjoberg R, Martinsson T
Br J Cancer . 2004 Aug; 91(6):1119-30. PMID: 15328517
Neuroblastoma is characterised by a lack of TP53 mutations and no other tumour suppressor gene consistently inactivated has yet been identified in this childhood cancer form. Characterisation of a new...
4.
Analyses of apoptotic regulators CASP9 and DFFA at 1P36.2, reveal rare allele variants in human neuroblastoma tumours
Abel F, Sjoberg R, Ejeskar K, Krona C, Martinsson T
Br J Cancer . 2002 Mar; 86(4):596-604. PMID: 11870543
The genes encoding Caspase-9 and DFF45 have both recently been mapped to chromosome region 1p36.2, that is a region alleged to involve one or several tumour suppressor genes in neuroblastoma...
5.
Fine mapping of a tumour suppressor candidate gene region in 1p36.2-3, commonly deleted in neuroblastomas and germ cell tumours
Ejeskar K, Sjoberg R, Abel F, Kogner P, Ambros P, Martinsson T
Med Pediatr Oncol . 2001 Jul; 36(1):61-6. PMID: 11464908
Background: A common genetic feature of neuroblastomas, which is also an important prognostic factor, is deletion of chromosome region 1p. The deletion of 1p often involves a deletion of varying...
6.
Fine mapping of the human preprocortistatin gene (CORT) to neuroblastoma consensus deletion region 1p36.3-->p36.2, but absence of mutations in primary tumors
Ejeskar K, Abel F, Sjoberg R, Backstrom J, Kogner P, Martinsson T
Cytogenet Cell Genet . 2000 Jul; 89(1-2):62-6. PMID: 10894940
The processed product of the human gene preprocortistatin, the peptide cortistatin-17 (hCST-17), bears a strong structural resemblance to the peptide somatostatin (SST), which has an identical receptor binding domain. CST...
7.
Gain of chromosome arm 17q is associated with unfavourable prognosis in neuroblastoma, but does not involve mutations in the somatostatin receptor 2(SSTR2) gene at 17q24
Abel F, Ejeskar K, Kogner P, Martinsson T
Br J Cancer . 1999 Dec; 81(8):1402-9. PMID: 10604740
Deletion of chromosome arm 1p and amplification of the MYCN oncogene are well-recognized genetic alterations in neuroblastoma cells. Recently, another alteration has been reported; gain of the distal part of...
8.
Variable expression and absence of mutations in p73 in primary neuroblastoma tumors argues against a role in neuroblastoma development
Ejeskar K, Sjoberg R, Kogner P, Martinsson T
Int J Mol Med . 1999 May; 3(6):585-9. PMID: 10341287
In neuroblastoma, a childhood tumor of neural crest, a tumor suppressor gene located at 1p36 has been implicated to play a major role in tumor aggressiveness and clinical prognosis. We...
9.
Loss of heterozygosity of 3p markers in neuroblastoma tumours implicate a tumour-suppressor locus distal to the FHIT gene
Ejeskar K, Aburatani H, Abrahamsson J, Kogner P, Martinsson T
Br J Cancer . 1998 Jul; 77(11):1787-91. PMID: 9667647
Neuroblastoma is a heterogeneous childhood tumour of the sympathetic nervous system, in which deletions of chromosomal region 1p and amplification of the MYCN oncogene correlate with aggressive tumour behaviour. However,...