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K E Ranaghan

Explore the profile of K E Ranaghan including associated specialties, affiliations and a list of published articles. Areas
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Articles 1
Citations 32
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1.
Callegari D, Ranaghan K, Woods C, Minari R, Tiseo M, Mor M, et al.
Chem Sci . 2018 May; 9(10):2740-2749. PMID: 29732058
Osimertinib is a third-generation inhibitor approved for the treatment of non-small cell lung cancer. It overcomes resistance to first-generation inhibitors by incorporating an acrylamide group which alkylates Cys797 of EGFR...