K E Davies
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Explore the profile of K E Davies including associated specialties, affiliations and a list of published articles.
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317
Citations
6953
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Recent Articles
1.
Van Rossen E, Liu Z, Blijweert D, Eysackers N, Mannaerts I, Schroyen B, et al.
Histochem Cell Biol
. 2013 Sep;
141(1):85-99.
PMID: 24043511
Hepatic stellate cells (HSCs) play an important role in several (patho)physiologic conditions in the liver. In response to chronic injury, HSCs are activated and change from quiescent to myofibroblast-like cells...
2.
Li Y, Huang J, Zhao Y, He J, Wang W, Davies K, et al.
Oncogene
. 2007 Mar;
26(42):6220-8.
PMID: 17384672
Though deletion of the long arm of chromosome 6 is one of the most common aberrations in tumors, its targeted gene(s) has not been convincingly identified. Using a functional screening...
3.
Hirst R, McCullagh K, Davies K
Acta Myol
. 2006 Apr;
24(3):209-16.
PMID: 16629055
Duchenne Muscular Dystrophy (DMD) is a devastating, progressive muscle wasting disease for which there is currently no effective treatment. DMD is caused by mutations in the dystrophin gene many of...
4.
Sewry C, Nowak K, Ehmsen J, Davies K
Neuromuscul Disord
. 2005 Oct;
15(11):779-85.
PMID: 16198105
Utrophin is an autosomal homologue of dystrophin, abnormal expression of which is responsible for X-linked Duchenne and Becker muscular dystrophy. In normal mature muscle utrophin is confined to blood vessels,...
5.
6.
Vargas J, Herpers B, McKie A, Gledhill S, McDonnell J, van den Heuvel M, et al.
Biochim Biophys Acta
. 2003 Sep;
1651(1-2):116-23.
PMID: 14499595
Iron has a variety of functions in cellular organisms ranging from electron transport and DNA synthesis to adenosine triphosphate (ATP) and neurotransmitter synthesis. Failure to regulate the homeostasis of iron...
7.
Anderson K, Potter A, Baban D, Davies K
Brain
. 2003 Jul;
126(Pt 9):2052-64.
PMID: 12847076
Autosomal recessive proximal spinal muscular atrophy (SMA) is a severe neurodegenerative disease of childhood causing weakness and wasting secondary to motor neuron dysfunction. Over 97% of cases are caused by...
8.
Cerletti M, Negri T, Cozzi F, Colpo R, Andreetta F, Croci D, et al.
Gene Ther
. 2003 Apr;
10(9):750-7.
PMID: 12704413
Utrophin is highly homologous and structurally similar to dystrophin, and in gene delivery experiments in mdx mice was able to functionally replace dystrophin. We performed mini-utrophin gene transfer in Golden...
9.
Squire S, Raymackers J, Vandebrouck C, Potter A, Tinsley J, Fisher R, et al.
Hum Mol Genet
. 2002 Dec;
11(26):3333-44.
PMID: 12471059
Duchenne muscular dystrophy results from the absence of dystrophin, a cytoskeletal protein. Previously, we have shown in a transgenic mouse model of the disease (mdx) that high levels of expression...
10.
Vargas J, Culetto E, Ponting C, Miguel-Aliaga I, Davies K, Sattelle D
Mech Dev
. 2002 Sep;
117(1-2):289-92.
PMID: 12204272
We have characterized the developmental expression pattern of the Caenorhabditis elegans homologue of the mouse ky gene. The Ky protein has a putative key function in muscle development and has...