K Deforche
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Explore the profile of K Deforche including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
440
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Recent Articles
1.
Kroneman A, Vennema H, Deforche K, v d Avoort H, Penaranda S, Oberste M, et al.
J Clin Virol
. 2011 Apr;
51(2):121-5.
PMID: 21514213
Background: Molecular techniques are established as routine in virological laboratories and virus typing through (partial) sequence analysis is increasingly common. Quality assurance for the use of typing data requires harmonization...
2.
Theys K, Deforche K, Libin P, Camacho R, Van Laethem K, Vandamme A
J Gen Virol
. 2010 Apr;
91(Pt 8):1898-1908.
PMID: 20410311
A better understanding of human immunodeficiency virus type 1 drug-resistance evolution under the selective pressure of combination treatment is important for the design of long-term effective treatment strategies. We applied...
3.
Deforche K, Camacho R, Van Laethem K, Lemey P, Rambaut A, Moreau Y, et al.
Bioinformatics
. 2007 Nov;
24(1):34-41.
PMID: 18024973
Motivation: HIV-1 antiviral resistance is a major cause of antiviral treatment failure. The in vivo fitness landscape experienced by the virus in presence of treatment could in principle be used...
4.
Deforche K, Camacho R, Grossman Z, Silander T, Soares M, Moreau Y, et al.
Infect Genet Evol
. 2006 Nov;
7(3):382-90.
PMID: 17127103
Interpretation of Human Immunodeficiency Virus 1 (HIV-1) genotypic drug resistance is still a major challenge in the follow-up of antiviral therapy in infected patients. Because of the high degree of...
5.
Deforche K, Silander T, Camacho R, Grossman Z, Soares M, Van Laethem K, et al.
Bioinformatics
. 2006 Oct;
22(24):2975-9.
PMID: 17021157
Human Immunodeficiency Virus-1 (HIV-1) antiviral resistance is a major cause of antiviral therapy failure and compromises future treatment options. As a consequence, resistance testing is the standard of care. Because...
6.
Paraskevis D, Deforche K, Abecasis A, Camacho R, Vandamme A
Infect Genet Evol
. 2005 Mar;
5(3):219-24.
PMID: 15737912
The increased complexity of HIV-1 genetic heterogeneity raises the issue for reliable classification and analysis of these sequences. Until now, bootscanning analysis has been the main method used for the...
7.
Paraskevis D, Deforche K, Lemey P, Magiorkinis G, Hatzakis A, Vandamme A
Bioinformatics
. 2004 Nov;
21(7):1274-5.
PMID: 15546940
We developed a software tool (SlidingBayes) for recombination analysis based on Bayesian phylogenetic inference. Sliding-Bayes provides a powerful approach for detecting potential recombination, especially between highly divergent sequences and complex...