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K Anastos

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Articles 43
Citations 754
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Recent Articles
1.
Brusca R, Hanna D, Wada N, Blankson J, Witt M, Jacobson L, et al.
HIV Med . 2019 Nov; 21(4):217-227. PMID: 31729142
Objectives: Elite controllers (ECs), viraemic controllers (VCs), and long-term nonprogressors (LTNPs) control HIV viral replication or maintain CD4 T-cell counts without antiretroviral therapy, but may have increased cardiovascular disease (CVD)...
2.
Kiefer E, Hoover D, Shi Q, Dusingize J, Sinayobye J, Anastos K
HIV Med . 2018 Aug; 19(10):734-744. PMID: 30160347
Objectives: African women are disproportionately affected by HIV infection and may experience non-AIDS-related complications associated with inflammation. High-sensitivity C-reactive protein (hsCRP), d-dimer and transthyretin have been examined as inflammatory markers...
3.
Pearce C, Stram D, Wiensch A, Frasco M, Kono N, Den Berg D, et al.
Int J HIV AIDS Res . 2018 Mar; 4(3):154-160. PMID: 29577081
Background: Clinical response to highly active antiretroviral therapy (HAART) varies among different populations. A portion of this variability may be due to variation in genes involved in the absorption, distribution,...
4.
Baxi S, Greenblatt R, Bacchetti P, Cohen M, DeHovitz J, Anastos K, et al.
Pharmacogenomics J . 2017 May; 18(2):245-250. PMID: 28462920
Higher exposure to tenofovir (TFV) increases the risk for kidney function decline, but the impact of genetic factors on TFV exposure is largely unknown. We investigated whether single-nucleotide polymorphisms (SNPs,...
5.
Vergara C, Thio C, Latanich R, Cox A, Kirk G, Mehta S, et al.
Genes Immun . 2017 Mar; 18(2):82-87. PMID: 28300059
Inflammasomes are multi-protein complexes integrating pathogen-triggered signaling leading to the generation of pro-inflammatory cytokines including interleukin-18 (IL-18). Hepatitis C virus (HCV) and human immunodeficiency virus (HIV) infections are associated with...
6.
Kuniholm M, Xie X, Anastos K, Xue X, Reimers L, French A, et al.
Int J Immunogenet . 2016 Oct; 43(6):369-375. PMID: 27774761
Human leucocyte antigen (HLA) genes play a central role in response to pathogens and in autoimmunity. Research to understand the effects of HLA genes on health has been limited because...
7.
Mutimura E, Shi Q, Hoover D, Anastos K, Rudakemwa E, Dusingize J, et al.
HIV Med . 2016 May; 17(10):724-727. PMID: 27161586
Objectives: The incidence of fractures appears to be increased in HIV-infected individuals. Methods: We assessed bone quality using quantitative ultrasound (QUS) in HIV-infected and uninfected Rwandan women. A Sunlight Omnisense...
8.
Peralta C, Scherzer R, Grunfeld C, ABraham A, Tien P, Devarajan P, et al.
HIV Med . 2013 Dec; 15(5):291-300. PMID: 24313986
Objectives: Chronic kidney disease (CKD) is common in HIV-infected individuals, and is associated with mortality in both the HIV-infected and general populations. Urinary markers of tubular injury have been associated...
9.
Kuniholm M, Anastos K, Kovacs A, Gao X, Marti D, Sette A, et al.
Genes Immun . 2013 May; 14(5):330-5. PMID: 23636221
Human leukocyte antigen (HLA) genotype has been associated with the probability of spontaneous clearance of hepatitis C virus (HCV). However, no prior studies have examined whether this relationship may be...
10.
Aumakhan B, Gange S, Beyrer C, Gaydos C, Minkoff H, Merenstein D, et al.
Int J STD AIDS . 2011 May; 22(5):273-7. PMID: 21571975
We identified demographic, clinical and biological determinants of herpes simplex virus type 2 (HSV-2) shedding among HIV-infected participants in the Women's HIV Interagency Study (WIHS). Cervicovaginal lavage (CVL) specimens from...