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K A Kirby

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Articles 30
Citations 163
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Recent Articles
1.
Gao X, McFadden W, Wen X, Emanuelli A, Lorson Z, Zheng H, et al.
bioRxiv . 2023 Dec; PMID: 38076946
Thermal shift assay (TSA) is a versatile biophysical technique for studying protein interactions. Here, we report a free, open-source software tool TSAR (Thermal Shift Analysis in R) to expedite and...
2.
Chitty K, Raubenheimer J, Cairns R, Kirby K, Buckley N
J Psychiatr Res . 2022 Feb; 148:103-109. PMID: 35123321
Deliberate self-poisoning (DSP) in adolescents is increasing dramatically. Life at school is one of the most important life influences for this age group. This study aimed to investigate whether the...
3.
Fisher C, Alexander J, Bhattacharya R, Rakita R, Kirby K, Boeckh M, et al.
Transpl Infect Dis . 2016 Mar; 18(3):372-80. PMID: 27004439
Background: Gastrointestinal (GI) cytomegalovirus (CMV) disease is the most common manifestation of tissue-invasive CMV infection in solid organ transplant (SOT) recipients, but the diagnostic yields of blood and tissue testing...
4.
Lee J, Hachiya A, Shin S, Lee J, Gatanaga H, Oka S, et al.
Clin Microbiol Infect . 2013 Mar; 19(6):E263-70. PMID: 23480551
Viral genotype assessment is important for effective clinical management of HIV-1 infected patients, especially when access and/or adherence to antiretroviral treatment is reduced. In this study, we describe development of...
5.
Michailidis E, Singh K, Ryan E, Hachiya A, Ong Y, Kirby K, et al.
Cell Mol Biol (Noisy-le-grand) . 2013 Jan; 58(1):187-95. PMID: 23273211
4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) is a highly potent inhibitor of HIV-1 reverse transcriptase (RT). We have previously shown that its exceptional antiviral activity stems from a unique mechanism of action that is...
6.
Ong Y, Kirby K, Hachiya A, Chiang L, Marchand B, Yoshimura K, et al.
Cell Mol Biol (Noisy-le-grand) . 2013 Jan; 58(1):71-9. PMID: 23273194
KD-247 is a humanized monoclonal antibody that targets the third hypervariable (V3) loop of gp120. It can efficiently neutralize a broad panel of clade B, but not non-clade B, HIV-1...
7.
Kirby K, Singh K, Michailidis E, Marchand B, Kodama E, Ashida N, et al.
Cell Mol Biol (Noisy-le-grand) . 2011 Mar; 57(1):40-6. PMID: 21366961
4' Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) is the most potent inhibitor of HIV reverse transcriptase (RT). We have recently named EFdA a Translocation Defective RT Inhibitor (TDRTI) because after its incorporation in the...
8.
Hakki M, Limaye A, Kim H, Kirby K, Corey L, Boeckh M
Bone Marrow Transplant . 2007 Apr; 39(11):687-93. PMID: 17401395
Limited data exist regarding the incidence and factors associated with outcome of invasive Pseudomonal infections in hematopoietic cell transplant (HCT). A retrospective analysis of cases of invasive Pseudomonas aeruginosa infection...
9.
Copp D, Godwin J, Kirby K, Limaye A
Am J Transplant . 2006 Oct; 6(11):2759-64. PMID: 17049063
Identifying clinical and radiographic factors that are associated with a specific etiology of pulmonary nodules (PNs) in solid-organ transplant (SOT) recipients might be helpful in guiding empiric therapy. Multivariable logistic...
10.
Chiu B, Gapstur S, Chow W, Kirby K, Lynch C, Cantor K
Int J Obes (Lond) . 2006 Feb; 30(6):940-7. PMID: 16446746
Objective: To investigate the association between obesity and risk of renal cell carcinoma and to examine whether the association is modified by physical activity. Subjects: A population-based case-control study of...