Jyotshna Kanungo
Overview
Explore the profile of Jyotshna Kanungo including associated specialties, affiliations and a list of published articles.
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35
Citations
361
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Recent Articles
1.
Kanungo J, Sorkin B, Krzykwa J, Mitchell C, Embry M, Spencer P, et al.
Expert Opin Drug Metab Toxicol
. 2024 Jul;
20(7):629-646.
PMID: 38984683
Areas Covered: This paper outlines the selection of NAMs, including in vitro assays using primary rat cortical neurons, zebrafish embryos, and . These assays aim to assess neurotoxic endpoints such...
2.
Gu Q, Kanungo J
Int J Mol Sci
. 2024 Mar;
25(6).
PMID: 38542432
The exact mechanisms of the development of autism, a multifactorial neurological disorder, are not clear. The pathophysiology of autism is complex, and investigations at the cellular and molecular levels are...
3.
Silva C, Kudlyk T, Tryndyak V, Twaddle N, Robinson B, Gu Q, et al.
J Appl Toxicol
. 2023 Jul;
43(12):1872-1882.
PMID: 37501093
Our previous study showed that sodium arsenite (200 mg/L) affected the nervous system and induced motor neuron development via the Sonic hedgehog pathway in zebrafish larvae. To gain more insight...
4.
Gu Q, Sarkar S, Raymick B, Kanungo J
Exp Biol Med (Maywood)
. 2023 May;
248(7):605-611.
PMID: 37208909
Tissue clearing refers to laboratory methods that make tissue transparent by chemical means. This approach allows the labeling, visualization, and analysis of specific targets without cutting the tissue into sections,...
5.
Kanungo J, Twaddle N, Silva C, Robinson B, Wolle M, Conklin S, et al.
Neurosci Lett
. 2023 Jan;
795:137042.
PMID: 36587726
The mechanism of inorganic arsenic-induced neurotoxicity at the cellular level is not known. In zebrafish, teratological effects of inorganic arsenic have been shown at various concentrations. Here, we used similar...
6.
Gu Q, Kanungo J
J Appl Toxicol
. 2021 May;
41(12):2083-2089.
PMID: 34002392
Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist. Used as an anesthetic, potential neurotoxic and cardiotoxic effects of ketamine in animal models have been reported. The underlying mechanisms of ketamine-induced toxicity...
7.
Robinson B, Gu Q, Kanungo J
Chem Res Toxicol
. 2021 Feb;
34(5):1198-1207.
PMID: 33566591
Recently, the United States Food and Drug Administration approved esketamine, the -enantiomer of ketamine, as a fast-acting therapeutic drug for treatment-resistant depression. Although ketamine is known as an -methyl-d-aspartate (NMDA)...
8.
Gu Q, Ali S, Kanungo J
J Appl Toxicol
. 2020 Jul;
41(2):256-264.
PMID: 32691447
Acetyl L-carnitine (ALCAR), a dietary supplement and an antioxidant, plays a vital role in the bioenergetic process that produces ATP. Although there are reports on antioxidant toxicity, there is no...
9.
Gu Q, Rodgers J, Robinson B, Kanungo J
Food Chem Toxicol
. 2020 Jul;
144:111559.
PMID: 32640352
There is a strong association between calcium channel blockers (CCBs) and heart failure. CCB toxicity is very common due to overdose and underlying medical conditions. CCBs also have been shown...
10.
Robinson B, Gu Q, Tryndyak V, Ali S, Dumas M, Kanungo J
J Appl Toxicol
. 2019 Oct;
40(2):257-269.
PMID: 31599005
Calcium channel blocker (CCB) poisoning is a common and sometimes life-threatening emergency. Our previous studies have shown that acetyl l-carnitine (ALCAR) prevents cardiotoxicity and developmental toxicity induced by verapamil, a...