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Justyna Sakowska

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Articles 18
Citations 184
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Recent Articles
1.
Zielinski M, Sakowska J, Iwaszkiewicz-Grzes D, Gliwinski M, Hennig M, Zalinska M, et al.
Int Immunopharmacol . 2024 Mar; 132:111919. PMID: 38554443
An imbalance between exaggerated autoaggressive T cell responses, primarily CD8 + T cells, and impaired tolerogenic mechanisms underlie the development of type 1 diabetes mellitus. Disease-modifying strategies, particularly immunotherapy focusing...
2.
Santosh Nirmala S, Kayani K, Gliwinski M, Hu Y, Iwaszkiewicz-Grzes D, Piotrowska-Mieczkowska M, et al.
Front Immunol . 2024 Jan; 14:1321228. PMID: 38283365
The initial idea of a distinct group of T-cells responsible for suppressing immune responses was first postulated half a century ago. However, it is only in the last three decades...
3.
Sakowska J, Glasner P, Dukat-Mazurek A, Rydz A, Zielinski M, Pellowska I, et al.
Transpl Immunol . 2023 May; 79:101852. PMID: 37196866
Background: Corneal transplantations (CTXs) are a vision-saving procedure. Routinely, while CTXs' survival rates remain high, the risk of graft failure increases significantly for repeated CTXs. The reason is an alloimmunization...
4.
Cezary Czarnogorski M, Sakowska J, Maziewski M, Zielinski M, Piekarska A, Obuchowski I, et al.
Immun Ageing . 2022 Nov; 19(1):51. PMID: 36324179
Background: Ageing is a complex phenomenon that leads to decreased proliferative activity, loss of function of the cells, and cellular senescence. Senescence of the immune system exacerbates individual's immune response,...
5.
Piotrowska M, Zielinski M, Tylicki L, Biedunkiewicz B, Kubanek A, Slizien Z, et al.
Front Immunol . 2022 Aug; 13:832924. PMID: 35935974
Clinical Trial Registration Number: www.ClinicalTrials.gov, identifier: NCT04 905 862.
6.
Stefanska K, Tomaszewicz M, Debska-Zielkowska J, Zamkowska D, Piekarska K, Sakowska J, et al.
Front Immunol . 2022 Aug; 13:868175. PMID: 35911739
Hypothesis: The activity of natural killer (NK) cells is considered an important factor for the tolerance of the fetus during pregnancy. The complications of pregnancy, such as hypertensive disorders (HDP),...
7.
Sakowska J, Arcimowicz L, Jankowiak M, Papak I, Markiewicz A, Dziubek K, et al.
Front Immunol . 2022 May; 13:793234. PMID: 35634292
Autoimmune disease results from the immune response against self-antigens, while cancer develops when the immune system does not respond to malignant cells. Thus, for years, autoimmunity and cancer have been...
8.
Zielinski M, Zalinska M, Iwaszkiewicz-Grzes D, Gliwinski M, Hennig M, Jazwinska-Curyllo A, et al.
Diabetes Obes Metab . 2022 Apr; 24(8):1534-1543. PMID: 35441440
Aims: Monotherapy with autologous expanded CD4 CD25 CD127 T regulatory cells (Tregs) or rituximab has been documented to slow disease progression in patients with recent-onset type 1 diabetes mellitus (T1DM)....
9.
Skrzypkowska M, Stasiak M, Sakowska J, Chmiel J, Maciejewska A, Bucinski A, et al.
Rheumatol Int . 2022 Feb; 42(4):609-619. PMID: 35179632
Rheumatoid arthritis is a severe chronic autoimmune disorder that results from pathological activation of immune cells and altered cytokine/chemokine network. The aim of our study was to evaluate concentrations of...
10.
Piekarska K, Urban-Wojciuk Z, Kurkowiak M, Pelikant-Malecka I, Schumacher A, Sakowska J, et al.
Nat Commun . 2022 Feb; 13(1):856. PMID: 35165293
Cell-based immunotherapies can provide safe and effective treatments for various disorders including autoimmunity, cancer, and excessive proinflammatory events in sepsis or viral infections. However, to achieve this goal there is...