Alpha 2.0
Login Register
» Authors » Justin Sudduth

Justin Sudduth

Explore the profile of Justin Sudduth including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 6
Citations 103
Followers 0
Related Specialties
Science
Parasitology
General Medicine
Top 10 Co-Authors
Juan U Rojo
Adebayo J Molehin
Afzal A Siddiqui
Weidong Zhang
David Carey
Workineh Torben
James F Papin
Arif J Siddiqui
Gul Ahmad
Souad R Sennoune
Published In
Ann N Y Acad Sci
PLoS One
Parasit Vectors
Parasitol Res
Front Immunol
Affiliations
Soon will be listed here.
Recent Articles
1.
Fifteen Years of Sm-p80-Based Vaccine Trials in Nonhuman Primates: Antibodies From Vaccinated Baboons Confer Protection and From and Identification of Putative Correlative Markers of Protection
Zhang W, Le L, Ahmad G, Molehin A, Siddiqui A, Torben W, et al.
Front Immunol . 2020 Jul; 11:1246. PMID: 32636844
Recent advances in systems biology have shifted vaccine development from a largely trial-and-error approach to an approach that promote rational design through the search for immune signatures and predictive correlates...
2.
Chronic whipworm infection exacerbates Schistosoma mansoni egg-induced hepatopathology in non-human primates
Le L, Khatoon S, Jimenez P, Peterson C, Kernen R, Zhang W, et al.
Parasit Vectors . 2020 Mar; 13(1):109. PMID: 32111243
Background: Schistosomiasis continues to inflict significant morbidity and mortality in the tropical and subtropical regions of the world. The disease endemicity overlaps with the transmission of other parasitic diseases. Despite...
3.
Sm-p80-based schistosomiasis vaccine: double-blind preclinical trial in baboons demonstrates comprehensive prophylactic and parasite transmission-blocking efficacy
Zhang W, Molehin A, Rojo J, Sudduth J, Ganapathy P, Kim E, et al.
Ann N Y Acad Sci . 2018 Aug; 1425(1):38-51. PMID: 30133707
Schistosomiasis is of public health importance to an estimated one billion people in 79 countries. A vaccine is urgently needed. Here, we report the results of four independent, double-blind studies...
4.
Sm-p80-based vaccine trial in baboons: efficacy when mimicking natural conditions of chronic disease, praziquantel therapy, immunization, and Schistosoma mansoni re-encounter
Siddiqui A, Molehin A, Zhang W, Ganapathy P, Kim E, Rojo J, et al.
Ann N Y Acad Sci . 2018 Jun; 1425(1):19-37. PMID: 29888790
Sm-p80-based vaccine efficacy for Schistosoma mansoni was evaluated in a baboon model of infection and disease. The study was designed to replicate a human vaccine implementation scenario for endemic regions...
5.
Cross-species prophylactic efficacy of Sm-p80-based vaccine and intracellular localization of Sm-p80/Sm-p80 ortholog proteins during development in Schistosoma mansoni, Schistosoma japonicum, and Schistosoma haematobium
Molehin A, Sennoune S, Zhang W, Rojo J, Siddiqui A, Herrera K, et al.
Parasitol Res . 2017 Oct; 116(11):3175-3188. PMID: 29026995
Schistosomiasis remains a major global health problem. Despite large-scale schistosomiasis control efforts, clear limitations such as possible emergence of drug resistance and reinfection rates highlight the need for an effective...
6.
Sm-p80-based schistosomiasis vaccine mediated epistatic interactions identified potential immune signatures for vaccine efficacy in mice and baboons
Rojo J, Melkus M, Kottapalli K, Okiya O, Sudduth J, Zhang W, et al.
PLoS One . 2017 Feb; 12(2):e0171677. PMID: 28192534
Schistosomiasis is a neglected parasitic disease of major public health concern as it affects over 250 million people in developing countries. Currently there is no licensed vaccine available against schistosomiasis....