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Justin Mower

Explore the profile of Justin Mower including associated specialties, affiliations and a list of published articles. Areas
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Citations 48
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Recent Articles
1.
Wu Y, Mower J, Ding X, Li O, Subramanian D, Cohen T
AMIA Annu Symp Proc . 2023 May; 2022:1163-1172. PMID: 37128462
Adverse event reports (AER) are widely used for post-market drug safety surveillance and drug repurposing, with the assumption that drugs with similar side-effects may have similar therapeutic effects also. In...
2.
Mower J, Bernstam E, Xu H, Myneni S, Subramanian D, Cohen T
AMIA Jt Summits Transl Sci Proc . 2022 Jul; 2022:349-358. PMID: 35854716
Although pharmaceutical products undergo clinical trials to profile efficacy and safety, some adverse drug reactions (ADRs) are only discovered after release to market. Post-market drug safety surveillance - pharmacovigilance -...
3.
Ding X, Mower J, Subramanian D, Cohen T
J Biomed Inform . 2021 Jun; 119:103833. PMID: 34111555
Adverse Drug Events (ADEs) are prevalent, costly, and sometimes preventable. Post-marketing drug surveillance aims to monitor ADEs that occur after a drug is released to market. Reports of such ADEs...
4.
Burkhardt H, Subramanian D, Mower J, Cohen T
AMIA Annu Symp Proc . 2020 Apr; 2019:992-1001. PMID: 32308896
The identification of drug-drug interactions (DDIs) is important for patient safety; yet, compared to other pharmacovigilance work, a limited amount of research has been conducted in this space. Recent work...
5.
Portanova J, Murray N, Mower J, Subramanian D, Cohen T
AMIA Annu Symp Proc . 2020 Apr; 2019:717-726. PMID: 32308867
Adverse event report (AER) data are a key source of signal for post marketing drug surveillance. The standard methodology to analyze AER data applies disproportionality metrics, which estimate the strength...
6.
Mower J, Cohen T, Subramanian D
Drug Saf . 2019 Oct; 43(1):67-77. PMID: 31646442
Introduction: As a result of the well documented limitations of data collected by spontaneous reporting systems (SRS), such as bias and under-reporting, a number of authors have evaluated the utility...
7.
Mower J, Subramanian D, Cohen T
J Am Med Inform Assoc . 2018 Jul; 25(10):1339-1350. PMID: 30010902
Objective: The aim of this work is to leverage relational information extracted from biomedical literature using a novel synthesis of unsupervised pretraining, representational composition, and supervised machine learning for drug...
8.
Mower J, Subramanian D, Shang N, Cohen T
AMIA Annu Symp Proc . 2017 Mar; 2016:1940-1949. PMID: 28269953
An important aspect of post-marketing drug surveillance involves identifying potential side-effects utilizing adverse drug event (ADE) reporting systems and/or Electronic Health Records. These data are noisy, necessitating identified drug/ADE associations...
9.
Almodovar J, Mower J, Banerjee A, Sarkar A, Ehrhart N, Kipper M
Biotechnol Bioeng . 2012 Aug; 110(2):609-18. PMID: 22903591
Cortical bone allografts suffer from high rates of failure due to poor integration with host tissue, leading to non-union, fracture, and infection following secondary procedures. Here, we report a method...