Justin L Madrigal
Overview
Explore the profile of Justin L Madrigal including associated specialties, affiliations and a list of published articles.
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7
Citations
94
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Recent Articles
1.
Madrigal J, Schoepp N, Xu L, Powell C, Delley C, Siltanen C, et al.
Proc Natl Acad Sci U S A
. 2022 Jan;
119(5).
PMID: 35074872
Cell-cell interactions are important to numerous biological systems, including tissue microenvironments, the immune system, and cancer. However, current methods for studying cell combinations and interactions are limited in scalability, allowing...
2.
Madrigal J, Stilhano R, Siltanen C, Tanaka K, Rezvani S, Morgan R, et al.
J Mater Chem B
. 2020 Apr;
4(43):6989-6999.
PMID: 32263565
Lentivectors are widely used for gene delivery and have been increasingly tested in clinical trials. However, achieving safe, localized, and sufficient gene expression remain key challenges for effective lentivectoral therapy....
3.
Madrigal J, Shams S, Stilhano R, Silva E
Biomater Sci
. 2018 Dec;
7(2):645-656.
PMID: 30534722
Gene therapy using viral vectors has been licensed for clinical use both in the European Union and the United States. Lentivectors (LV) and adeno-associated vectors (AAV) are two promising and...
4.
Madrigal J, Sharma S, Campbell K, Stilhano R, Gijsbers R, Silva E
Acta Biomater
. 2018 Feb;
69:265-276.
PMID: 29398644
Statement Of Significance: Genetic therapeutics hold considerable potential for the treatment of diseases and disorders including ischemic cardiovascular diseases. To realize this potential, genetic vectors must be precisely and efficiently...
5.
Madrigal J, Stilhano R, Silva E
Tissue Eng Part B Rev
. 2017 Feb;
23(4):347-361.
PMID: 28166711
Gene therapy is a promising strategy for musculoskeletal tissue repair and regeneration where local and sustained expression of proteins and/or therapeutic nucleic acids can be achieved. However, the musculoskeletal tissues...
6.
Williams P, Campbell K, Gharaviram H, Madrigal J, Silva E
Ann Biomed Eng
. 2016 Dec;
45(4):1003-1014.
PMID: 27904998
Sphingosine-1-phosphate (S1P), a bioactive lipid, is a potent candidate for treatment of ischemic vascular disease. However, designing biomaterial systems for the controlled release of S1P to achieve therapeutic angiogenesis presents...
7.
Stilhano R, Madrigal J, Wong K, Williams P, Martin P, Yamaguchi F, et al.
J Control Release
. 2016 Jul;
237:42-9.
PMID: 27374631
Hydrogels are an especially appealing class of biomaterials for gene delivery vehicles as they can be introduced into the body with minimally invasive procedures and are often applied in tissue...