Justin E Aldridge
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Explore the profile of Justin E Aldridge including associated specialties, affiliations and a list of published articles.
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11
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Recent Articles
1.
Aldridge J, Meyer A, Seidler F, Slotkin T
Environ Health Perspect
. 2005 Aug;
113(8):1027-31.
PMID: 16079074
Exposure to chlorpyrifos (CPF) alters neuronal development of serotonin (5HT) and dopamine systems, and we recently found long-term alterations in behaviors related to 5HT function. To characterize the synaptic mechanisms...
2.
Aldridge J, Levin E, Seidler F, Slotkin T
Environ Health Perspect
. 2005 May;
113(5):527-31.
PMID: 15866758
Developmental exposure to chlorpyrifos (CPF) causes persistent changes in serotonergic (5HT) systems. We administered 1 mg/kg/day CPF to rats on postnatal days 1-4, a regimen below the threshold for systemic...
3.
Kreider M, Aldridge J, Cousins M, Oliver C, Seidler F, Slotkin T
Neuropsychopharmacology
. 2005 Apr;
30(10):1841-55.
PMID: 15841102
Glucocorticoids are the consensus treatment for the prevention of respiratory distress in preterm infants, but there is evidence for increased incidence of neurodevelopmental disorders as a result of their administration....
4.
Meyer A, Seidler F, Aldridge J, Slotkin T
Toxicol Appl Pharmacol
. 2005 Feb;
203(2):154-66.
PMID: 15710176
Exposure to apparently unrelated neurotoxicants can nevertheless converge on common neurodevelopmental events. We examined the long-term effects of developmental exposure of rats to terbutaline, a beta-adrenoceptor agonist used to arrest...
5.
Aldridge J, Meyer A, Seidler F, Slotkin T
Toxicol Appl Pharmacol
. 2005 Feb;
203(2):132-44.
PMID: 15710174
Developmental exposure to unrelated neurotoxicants can nevertheless produce similar neurobehavioral outcomes. We examined the effects of developmental exposure to terbutaline, a tocolytic beta2-adrenoceptor agonist used to arrest preterm labor, and...
6.
Beer A, Slotkin T, Seidler F, Aldridge J, Yanai J
Neuropsychopharmacology
. 2004 Oct;
30(1):156-65.
PMID: 15496940
A major objective in identifying the mechanisms underlying neurobehavioral teratogenicity is the possibility of designing therapies that reverse or offset drug- or toxicant-induced neural damage. In our previous studies, we...
7.
Slotkin T, Seidler F, Qiao D, Aldridge J, Tate C, Cousins M, et al.
Neuropsychopharmacology
. 2004 Aug;
30(1):129-44.
PMID: 15316571
Studies in developing rodents indicate that nicotine is a neuroteratogen that disrupts brain development by stimulating nicotinic acetylcholine receptors (nAChRs) that control neural cell replication and differentiation. We administered nicotine...
8.
Meyer A, Seidler F, Aldridge J, Tate C, Cousins M, Slotkin T
Environ Health Perspect
. 2004 Mar;
112(3):295-301.
PMID: 14998743
Developmental exposure to chlorpyrifos (CPF) alters the function of a wide variety of neural systems. In the present study we evaluated the effects in adulthood of CPF exposure of rats...
9.
Aldridge J, Seidler F, Slotkin T
Environ Health Perspect
. 2004 Feb;
112(2):148-55.
PMID: 14754568
During brain development, serotonin (5HT) provides essential neurotrophic signals, and in earlier work, we found that developmental exposure to chlorpyrifos (CPF) elicits short-term changes in 5HT systems. In the present...
10.
Aldridge J, Seidler F, Meyer A, Thillai I, Slotkin T
Environ Health Perspect
. 2003 Nov;
111(14):1736-43.
PMID: 14594624
During brain development, serotonin (5HT) provides essential neurotrophic signals. In the present study, we evaluated whether the developmental neurotoxicity of chlorpyrifos (CPF) involves effects on 5HT signaling, as a potential...