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Justin D Radolf

Explore the profile of Justin D Radolf including associated specialties, affiliations and a list of published articles. Areas
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Articles 119
Citations 5383
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Recent Articles
1.
Day S, Carter A, Lloyd A, Sena A, Radolf J, Tucker J
Sex Reprod Health Matters . 2025 Mar; :1-26. PMID: 40052273
Amidst resurging syphilis infection rates, increasing efforts are being made towards development of a syphilis vaccine. This study aims to identify barriers and facilitators of syphilis vaccine trial participation among...
2.
Delgado K, Caimano M, Orbe I, Vicente C, La Vake C, Grassmann A, et al.
PLoS Pathog . 2024 Dec; 20(12):e1012443. PMID: 39715273
The global resurgence of syphilis has created a potent stimulus for vaccine development. To identify potentially protective antibodies against Treponema pallidum (TPA), we used Pyrococcus furiosus thioredoxin (PfTrx) to display...
3.
Delgado K, Vicente C, Hennelly C, Aghakhanian F, Parr J, Claffey K, et al.
mBio . 2024 Nov; 16(1):e0325324. PMID: 39611839
Importance: Syphilis, a sexually transmitted infection caused by (), remains a pressing threat to global public health. has a remarkable and still poorly understood ability to disseminate rapidly from the...
4.
Delgado K, Vicente C, Hennelly C, Aghakhanian F, Parr J, Claffey K, et al.
bioRxiv . 2024 Nov; PMID: 39484466
Syphilis is a sexually transmitted infection caused by the highly invasive and immunoevasive spirochetal pathogen subsp. (). Untreated syphilis can lead to infection of multiple organ systems, including the central...
5.
Sena A, Matoga M, Yang L, Lopez-Medina E, Aghakhanian F, Chen J, et al.
Lancet Microbe . 2024 Aug; 5(9):100871. PMID: 39181152
Background: The increase in syphilis rates worldwide necessitates development of a vaccine with global efficacy. We aimed to explore Treponema pallidum subspecies pallidum (TPA) molecular epidemiology essential for vaccine research...
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Delgado K, Caimano M, Orbe I, Vicente C, La Vake C, Grassmann A, et al.
bioRxiv . 2024 Aug; PMID: 39131275
The global resurgence of syphilis has created a potent stimulus for vaccine development. To identify potentially protective antibodies (Abs) against (), we used thioredoxin (Trx) to display extracellular loops (ECLs)...
8.
Liu A, Giacani L, Hawley K, Cameron C, Sena A, Konda K, et al.
Sex Transm Dis . 2024 Jul; 51(11):e49-e53. PMID: 39037061
The New Pathways in Syphilis Vaccine Development meeting was held before the start of the STI & HIV 2023 World Congress as a pre-meeting symposium to highlight recent advances in...
9.
Salazar J, Vargas-Cely F, Garcia-Luna J, Ramirez L, Bettin E, Romero-Rosas N, et al.
PLoS One . 2024 Jul; 19(7):e0307600. PMID: 39028747
Background: Venereal syphilis, caused by the spirochete Treponema pallidum subsp. pallidum (TPA), is surging worldwide, underscoring the need for a vaccine with global efficacy. Vaccine development requires an understanding of...
10.
Yang L, Zhang X, Chen W, Sena A, Zheng H, Jiang Y, et al.
J Infect Dis . 2024 Jun; 230(6):e1322-e1333. PMID: 38884588
Background: The global resurgence of syphilis necessitates vaccine development. Methods: We collected ulcer exudates and blood from 17 participants with primary syphilis (PS) and skin biopsies and blood from 51...