Jushuo Wang
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Explore the profile of Jushuo Wang including associated specialties, affiliations and a list of published articles.
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27
Citations
587
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Recent Articles
1.
Wang J, Fan Y, Dube S, Benz P, Dube D, Sanger J, et al.
Cytoskeleton (Hoboken)
. 2024 Nov;
PMID: 39526308
Previous reports from our laboratory describing the formation of myofibrils in cultured embryonic cardiac and skeletal muscle cells have proposed that myofibrillogenesis occurs in three steps of increasing protein organization:...
2.
Welchons M, Wang J, Fan Y, Sanger J, Sanger J
Cytoskeleton (Hoboken)
. 2023 Sep;
80(11-12):461-471.
PMID: 37767774
Myofibrils in vertebrate skeletal muscle are organized in aligned arrays of filaments formed from multiple protein components. Despite considerable information describing individual proteins, how they assemble de novo into mature...
3.
Wang J, Fan Y, Sanger J, Sanger J
Cytoskeleton (Hoboken)
. 2022 Sep;
79(12):122-132.
PMID: 36125330
A three-step model has been proposed to describe myofibril assembly in vertebrate cardiac and skeletal muscle cells beginning with premyofibrils, followed by nascent myofibrils, and ending as mature myofibrils (reviewed...
4.
Wang J, Fan Y, Mittal B, Sanger J, Sanger J
Cytoskeleton (Hoboken)
. 2022 Sep;
79(9-11):105-115.
PMID: 36085566
The α-actin mutation G15R in the nucleotide-binding pocket of skeletal muscle, causes severe actin myopathy in human skeletal muscles. Expressed in cultured embryonic quail skeletal myotubes, YFP-G15R-α-actin incorporates in sarcomeres...
5.
Wang J, Fan Y, Wang C, Dube S, Poiesz B, Dube D, et al.
Cytoskeleton (Hoboken)
. 2022 May;
78(10-12):461-491.
PMID: 35502133
Details of sarcomeric protein assembly during de novo myofibril formation closely resemble myofibrillogenesis in skeletal and cardiac myocytes in birds, rodents, and zebrafish. The arrangement of proteins during myofibrillogenesis follows...
6.
Dube D, Wang J, Fan Y, Dube S, Abbott L, Sanger J, et al.
Cytoskeleton (Hoboken)
. 2021 Oct;
78(8):375-390.
PMID: 34698442
In the three-step myofibrillogenesis model, mature myofibrils are formed through two intermediate structures: premyofibrils and nascent myofibrils. We have recently reported that several inhibitors of the Ubiquitin Proteosome System, for...
7.
Wang J, Fan Y, Dube S, Agassy N, Dube D, Sanger J, et al.
Cytoskeleton (Hoboken)
. 2020 Oct;
77(10):456-479.
PMID: 33124174
De novo assembly of myofibrils in vertebrate cross-striated muscles progresses in three distinct steps, first from a minisarcomeric alignment of several nonmuscle and muscle proteins in premyofibrils, followed by insertions...
8.
White J, Wang J, Fan Y, Dube D, Sanger J, Sanger J
Anat Rec (Hoboken)
. 2018 Dec;
301(12):2067-2079.
PMID: 30537042
The formation of myofibrils was analyzed in neonatal mouse cardiomyocytes grown in culture and stained with fluorescent antibodies directed against myofibrillar proteins. The cardiomyocyte cultures also were exposed to siRNA...
9.
Dube D, Dube S, Shrestha R, Abbott L, Randhawa S, Muthu V, et al.
Cytoskeleton (Hoboken)
. 2018 Sep;
75(10):437-449.
PMID: 30255988
The chicken has been used since the 1980s as an animal model for developmental studies regarding tropomyosin isoform diversity in striated muscles, however, the pattern of expression of transcripts as...
10.
Wang J, Fan Y, Sanger J, Sanger J
Cytoskeleton (Hoboken)
. 2018 May;
75(8):339-351.
PMID: 29781105
De novo assembly of contractile myofibrils begins with the formation of premyofibrils where filaments of non-muscle myosin (NM II), and actin organize in sarcomeric patterns with Z-Bodies containing muscle-specific alpha-actinin....