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» Authors » Jurgen Serth

Jurgen Serth

Explore the profile of Jurgen Serth including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 47
Citations 1110
Followers 0
Related Specialties
Oncology
Urology
Biochemistry
Top 10 Co-Authors
Markus A Kuczyk
Jorg Hennenlotter
Arnulf Stenzl
Inga Peters
Hossein Tezval
Axel S Merseburger
Natalia Dubrowinskaja
Sandra Waalkes
Faranaz Atschekzei
Stefan Machtens
Published In
Oncol Rep
Prostate
BMC Cancer
World J Urol
Int J Mol Sci
Affiliations
Soon will be listed here.
Recent Articles
11.
Rho GDP dissociation inhibitor-β in renal cell carcinoma
von Klot C, Dubrowinskaja N, Peters I, Hennenlotter J, Merseburger A, Stenzl A, et al.
Oncol Lett . 2017 Dec; 14(6):8190-8196. PMID: 29250194
Rho GDP dissociation inhibitor-β (ARHGDIB) is an important mediator of cell signaling. The expression of ARHGDIB is associated with tumor growth and metastasis in a variety of non-genitourinary cancers; however,...
12.
Tumor Specific Epigenetic Silencing of Corticotropin Releasing Hormone -Binding Protein in Renal Cell Carcinoma: Association of Hypermethylation and Metastasis
Tezval H, Dubrowinskaja N, Peters I, Reese C, Serth K, Atschekzei F, et al.
PLoS One . 2016 Oct; 11(10):e0163873. PMID: 27695045
The relevance of Corticotropin Releasing Hormone (CRH)-system in human malignancies is a question of growing interest. Here we investigated hypermethylation and epigenetic silencing of the CRH-Binding Protein (CRHBP) gene in...
13.
Signatures of Adverse Pathological Features, Androgen Insensitivity and Metastatic Potential in Prostate Cancer
Tolkach Y, Merseburger A, Herrmann T, Kuczyk M, Serth J, Imkamp F
Anticancer Res . 2015 Sep; 35(10):5443-51. PMID: 26408707
Background/aim: The genetic characterization of prostate tumors is important for personalized therapy. The aim of the present study was to investigate the role of previously described prostate cancer-related genes in...
14.
Decreased mRNA expression of GATA1 and GATA2 is associated with tumor aggressiveness and poor outcome in clear cell renal cell carcinoma
Peters I, Dubrowinskaja N, Tezval H, Kramer M, von Klot C, Hennenlotter J, et al.
Target Oncol . 2014 Sep; 10(2):267-75. PMID: 25230694
GATA-binding proteins 1 (GATA1) and 2 (GATA2) are zinc-finger transcription factors and belong to the GATA family proteins 1-6. GATA1 interacts with the TP53 tumor suppressor gene, and both GATAs...
15.
DNA methylation biomarkers predict progression-free and overall survival of metastatic renal cell cancer (mRCC) treated with antiangiogenic therapies
Peters I, Dubrowinskaja N, Abbas M, Seidel C, Kogosov M, Scherer R, et al.
PLoS One . 2014 Mar; 9(3):e91440. PMID: 24633192
VEGF-targeted therapy increases both the progression-free (PFS) and overall survival (OS) of patients with metastasized renal cell cancer (mRCC). Identification of molecular phenotypes of RCC could improve risk-stratification and the...
16.
Decreased GATA5 mRNA expression associates with CpG island methylation and shortened recurrence-free survival in clear cell renal cell carcinoma
Peters I, Dubrowinskaja N, Kogosov M, Abbas M, Hennenlotter J, von Klot C, et al.
BMC Cancer . 2014 Feb; 14:101. PMID: 24533449
Background: GATA-5, a zinc-finger transcription factor and member of the GATA family proteins 1-6, is known to be involved in cellular differentiation. We recently found that tumor-specific hypermethylation of the...
17.
Neurofilament Heavy polypeptide CpG island methylation associates with prognosis of renal cell carcinoma and prediction of antivascular endothelial growth factor therapy response
Dubrowinskaja N, Gebauer K, Peters I, Hennenlotter J, Abbas M, Scherer R, et al.
Cancer Med . 2014 Jan; 3(2):300-9. PMID: 24464810
Neurofilament Heavy polypeptid (NEFH) belongs to the group of type IV intermediate filament proteins. DNA methylation of the NEFH promoter and loss of expression have previously been shown to activate...
18.
Reduced mRNA expression level of corticotropin-releasing hormone-binding protein is associated with aggressive human kidney cancer
Tezval H, Atschekzei F, Peters I, Waalkes S, Hennenlotter J, Stenzl A, et al.
BMC Cancer . 2013 Apr; 13:199. PMID: 23607589
Background: Significance of Urocortin (Ucn or UcnI), Ucn2, Ucn3 and their receptors, Corticotropin Releasing Factor Receptor 1 and 2 (CRFR1 and CRFR2), and the binding protein, Corticotropin-Releasing Hormone-Binding Protein (CRHBP)...
19.
Association of single nucleotide polymorphisms on chromosome 9p21.3 with cardiovascular death in kidney transplant recipients
Melk A, Schildhorn C, Homme M, Knoch M, Schmidt B, Serth J, et al.
Transplantation . 2013 Feb; 95(7):928-32. PMID: 23388737
Background: Recipient death is a leading cause for renal allograft loss. Cardiovascular mortality is the most important cause of death among this patient group. Single nucleotide polymorphisms (SNPs) in a...
20.
A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease
Olama A, Kote-Jarai Z, Schumacher F, Wiklund F, Berndt S, Benlloch S, et al.
Hum Mol Genet . 2012 Oct; 22(2):408-15. PMID: 23065704
Genome-wide association studies (GWAS) have identified multiple common genetic variants associated with an increased risk of prostate cancer (PrCa), but these explain less than one-third of the heritability. To identify...