Jurgen Sandkuhler
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Explore the profile of Jurgen Sandkuhler including associated specialties, affiliations and a list of published articles.
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62
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2976
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Recent Articles
11.
Prosenz J, Kloimstein H, Thaler U, Drdla-Schutting R, Sandkuhler J, Gustorff B
J Clin Neurosci
. 2017 Mar;
40:195-197.
PMID: 28279552
Mechanism-based therapy for chronic pain is desperately needed. Recent basic science research demonstrated that remifentanil can reverse long-term potentiation at C-fiber synapses in the dorsal horn of rats. In this...
12.
13.
Gerhold K, Drdla-Schutting R, Honsek S, Forsthuber L, Sandkuhler J
J Neurosci
. 2015 Jul;
35(26):9580-94.
PMID: 26134641
Due to its distinct pharmacological profile and lower incidence of adverse events compared with other opioids, buprenorphine is considered a safe option for pain and substitution therapy. However, despite its...
14.
Clark A, Gruber-Schoffnegger D, Drdla-Schutting R, Gerhold K, Malcangio M, Sandkuhler J
J Neurosci
. 2015 Mar;
35(11):4552-70.
PMID: 25788673
Synaptic plasticity is thought to be initiated by neurons only, with the prevailing view assigning glial cells mere specify supportive functions for synaptic transmission and plasticity. We now demonstrate that...
15.
Honsek S, Seal R, Sandkuhler J
Pain
. 2015 Jan;
156(2):243-251.
PMID: 25599445
Distinct subsets of sensory nerve fibres are involved in mediating mechanical and thermal pain hypersensitivity. They may also differentially respond to analgesics. Heat-sensitive C-fibres, for example, are thought to respond...
16.
Draxler P, Honsek S, Forsthuber L, Hadschieff V, Sandkuhler J
J Neurosci
. 2014 Sep;
34(36):12015-28.
PMID: 25186747
Sensory nerve fibers differ not only with respect to their sensory modalities and conduction velocities, but also in their relative roles for pain hypersensitivity. It is presently largely unknown which...
17.
Bradl M, Kanamori Y, Nakashima I, Misu T, Fujihara K, Lassmann H, et al.
Nat Rev Neurol
. 2014 Jul;
10(9):529-36.
PMID: 25072195
Terrible, agonizing, wretched, sickening and unbearable--these are words frequently used by patients with neuromyelitis optica (NMO) to describe a very common symptom of their disease: pain. More than 80% of...
18.
Xanthos D, Sandkuhler J
Nat Rev Neurosci
. 2013 Nov;
15(1):43-53.
PMID: 24281245
The CNS is endowed with an elaborated response repertoire termed 'neuroinflammation', which enables it to cope with pathogens, toxins, traumata and degeneration. On the basis of recent publications, we deduce...
19.
Leitner J, Westerholz S, Heinke B, Forsthuber L, Wunderbaldinger G, Jager T, et al.
PLoS One
. 2013 Sep;
8(8):e73370.
PMID: 24009748
Adequate pain sensitivity requires a delicate balance between excitation and inhibition in the dorsal horn of the spinal cord. This balance is severely impaired in neuropathy leading to enhanced pain...
20.
Naka A, Gruber-Schoffnegger D, Sandkuhler J
Pain
. 2013 May;
154(8):1333-42.
PMID: 23707311
Current concepts of memory storage are largely based on Hebbian-type synaptic long-term potentiation induced by concurrent activity of pre- and postsynaptic neurons. Little is known about non-Hebbian synaptic plasticity, which,...