Jurgen Sandkuhler
Overview
Explore the profile of Jurgen Sandkuhler including associated specialties, affiliations and a list of published articles.
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62
Citations
2976
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Recent Articles
1.
Mussetto V, Teuchmann H, Heinke B, Trofimova L, Sandkuhler J, Drdla-Schutting R, et al.
J Pain
. 2023 May;
24(9):1664-1680.
PMID: 37150382
Opioids are powerful analgesics commonly used in pain management. However, opioids can induce complex neuroadaptations, including synaptic plasticity, that ultimately drive severe side effects, such as pain hypersensitivity and strong...
2.
Mussetto V, Moen A, Trofimova L, Sandkuhler J, Hogri R
Front Cell Neurosci
. 2023 Apr;
17:1163171.
PMID: 37082205
The clinical burden faced by chronic pain patients is compounded by affective comorbidities, such as depression and anxiety disorders. Emerging evidence suggests that reactive glial cells in the spinal cord...
3.
Hogri R, Baltov B, Drdla-Schutting R, Mussetto V, Raphael H, Trofimova L, et al.
Mol Pain
. 2023 Jan;
19:17448069231156657.
PMID: 36717755
The aversive aspect of pain constitutes a major burden faced by pain patients. This has been recognized by the pain research community, leading to the development of novel methods focusing...
4.
Hogri R, Teuchmann H, Heinke B, Holzinger R, Trofimova L, Sandkuhler J
J Neurosci
. 2022 Jun;
42(27):5373-5388.
PMID: 35667849
Pain and emotion are strongly regulated by neurons in the central nucleus of the amygdala (CeA), a major output of the limbic system; yet, the neuronal signaling pathways underlying this...
5.
Teuchmann H, Hogri R, Heinke B, Sandkuhler J
J Pain
. 2022 Mar;
23(8):1410-1426.
PMID: 35339662
The lateral parabrachial nucleus (LPBN) plays an important role in the processing and establishment of pain aversion. It receives direct input from the superficial dorsal horn and forms reciprocal connections...
6.
Draxler P, Moen A, Galek K, Boghos A, Ramazanova D, Sandkuhler J
Front Pain Res (Lausanne)
. 2022 Mar;
2:672711.
PMID: 35295455
In pain patients affective and motivational reactions as well as impairment of daily life activities dominate the clinical picture. In contrast, many rodent pain models have been established on the...
7.
Kronschlager M, Siegert A, Resch F, Rajendran P, Khakh B, Sandkuhler J
Glia
. 2021 Mar;
69(7):1749-1766.
PMID: 33694249
Astrocytes are indispensable for proper neuronal functioning. Given the diverse needs of neuronal circuits and the variety of tasks astrocytes perform, the perceived homogeneous nature of astrocytes has been questioned....
8.
Hadschieff V, Drdla-Schutting R, Springer D, Siegert A, Schroeder H, Sandkuhler J
Pain
. 2020 Apr;
161(9):2022-2034.
PMID: 32345917
Withdrawal from systemic opioids can induce long-term potentiation (LTP) at spinal C-fibre synapses ("opioid-withdrawal-LTP"). This is considered to be a cellular mechanism underlying opioid withdrawal-induced hyperalgesia, which is a major...
9.
Reischer G, Heinke B, Sandkuhler J
Mol Pain
. 2020 Apr;
16:1744806920917249.
PMID: 32264753
No abstract available.
10.
Drdla-Schutting R, Heinl C, Hadschieff V, Sandkuhler J
Pain
. 2019 Aug;
160(12):2819-2828.
PMID: 31433351
Opioids are the most powerful analgesics available to date. However, they may also induce adverse effects including paradoxical opioid-induced hyperalgesia. A mechanism that might underlie opioid-induced hyperalgesia is the amplification...