Jurgen Daut
Overview
Explore the profile of Jurgen Daut including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
1438
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Recent Articles
1.
The Phosphodiesterase Inhibitor IBMX Blocks the Potassium Channel THIK-1 from the Extracellular Side
Zou X, Conrad L, Koschinsky K, Schlichthorl G, Preisig-Muller R, Netz E, et al.
Mol Pharmacol
. 2020 Jul;
98(2):143-155.
PMID: 32616523
The two-pore domain potassium channel (K-channel) THIK-1 has several predicted protein kinase A (PKA) phosphorylation sites. In trying to elucidate whether THIK-1 is regulated via PKA, we expressed THIK-1 channels...
2.
Renigunta V, Schlichthorl G, Daut J
Pflugers Arch
. 2015 Mar;
467(5):867-94.
PMID: 25791628
Over the last decade, we have seen an enormous increase in the number of experimental studies on two-pore-domain potassium channels (K2P-channels). The collection of reviews and original articles compiled for...
3.
Budde T, Daut J, Kurtz A, Pape H
Pflugers Arch
. 2015 Mar;
467(5):865-6.
PMID: 25771953
No abstract available.
4.
Kilisch M, Lytovchenko O, Schwappach B, Renigunta V, Daut J
Pflugers Arch
. 2015 Jan;
467(5):1105-20.
PMID: 25559843
The intracellular transport of membrane proteins is controlled by trafficking signals: Short peptide motifs that mediate the contact with COPI, COPII or various clathrin-associated coat proteins. In addition, many membrane...
5.
Bodnar M, Schlichthorl G, Daut J
Pflugers Arch
. 2014 Dec;
467(5):1069-79.
PMID: 25539776
We studied the potassium current flowing through TREK-1 channels in rat cardiac ventricular myocytes. We separated the TREK-1 current from other current components by blocking most other channels with a...
6.
Renigunta V, Fischer T, Zuzarte M, Kling S, Zou X, Siebert K, et al.
Mol Biol Cell
. 2014 Apr;
25(12):1877-91.
PMID: 24743596
The endosomal SNARE protein syntaxin-8 interacts with the acid-sensitive potassium channel TASK-1. The functional relevance of this interaction was studied by heterologous expression of these proteins (and mutants thereof) in...
7.
Renigunta V, Zou X, Kling S, Schlichthorl G, Daut J
Pflugers Arch
. 2013 Dec;
466(9):1735-45.
PMID: 24297522
THIK-2 belongs to the 'silent' channels of the two-pore-domain potassium channel family. It is highly expressed in many nuclei of the brain but has so far resisted all attempts at...
8.
Rinne S, Renigunta V, Schlichthorl G, Zuzarte M, Bittner S, Meuth S, et al.
Pflugers Arch
. 2013 Nov;
466(8):1559-70.
PMID: 24196565
We have identified a novel splice variant of the human and rat two-pore domain potassium (K2P) channel TREK-1. The splice variant TREK-1e results from skipping of exon 5, which causes...
9.
Anders C, Higuchi Y, Koschinsky K, Bartel M, Schumacher B, Thiel P, et al.
Chem Biol
. 2013 Apr;
20(4):583-93.
PMID: 23601647
Small-molecule stabilization of protein-protein interactions is an emerging field in chemical biology. We show how fusicoccanes, originally identified as fungal toxins acting on plants, promote the interaction of 14-3-3 proteins...
10.
Schiekel J, Lindner M, Hetzel A, Wemhoner K, Renigunta V, Schlichthorl G, et al.
Cardiovasc Res
. 2012 Sep;
97(1):97-105.
PMID: 22977011
Aims: The two-pore-domain potassium channel TASK-1 is robustly inhibited by the activation of receptors coupled to the Gα(q) subgroup of G-proteins, but the signal transduction pathway is still unclear. We...