Jurgen C Frolich
Overview
Explore the profile of Jurgen C Frolich including associated specialties, affiliations and a list of published articles.
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50
Citations
841
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Recent Articles
1.
Tsikas D, Hanff E, Bollenbach A, Kruger R, Pham V, Chobanyan-Jurgens K, et al.
Amino Acids
. 2018 May;
50(7):799-821.
PMID: 29728915
We recently found that renal carbonic anhydrase (CA) is involved in the reabsorption of inorganic nitrite (NO), an abundant reservoir of nitric oxide (NO) in tissues and cells. Impaired NO...
2.
Tsikas D, Rothmann S, Schneider J, Gutzki F, Beckmann B, Frolich J
Anal Biochem
. 2016 Aug;
524:31-44.
PMID: 27530652
Here, we report the simultaneous derivatization and quantification of malondialdehyde (MDA) and 4-hydroxy-2-nonenal (HNE) in human plasma by GC-MS/MS using [1,3-H]-MDA (d-MDA) and [9,9,9-H]-HNE (d-HNE) as the internal standards, respectively....
3.
Tsikas D, Rothmann S, Schneider J, Suchy M, Trettin A, Modun D, et al.
J Chromatogr B Analyt Technol Biomed Life Sci
. 2015 Nov;
1019:95-111.
PMID: 26522895
Malondialdehyde (MDA, CH2(CHO)2) is one of the best investigated and most frequently measured biomarkers of lipid peroxidation in biological fluids, a constituent of the so called thiobarbituric acid reactive substances...
4.
Schneider J, Rothmann S, Schroder F, Langen J, Lucke T, Mariotti F, et al.
Amino Acids
. 2015 Jul;
47(9):1961-74.
PMID: 26123989
Despite saturation of nitric oxide (NO) synthase (NOS) by its substrate L-arginine (Arg), oral and intravenous supplementation of Arg may enhance NO synthesis, a phenomenon known as "The L-arginine paradox"....
5.
Kayacelebi A, Langen J, Weigt-Usinger K, Chobanyan-Jurgens K, Mariotti F, Schneider J, et al.
Amino Acids
. 2015 Jun;
47(9):1893-908.
PMID: 26031828
Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide (NO) synthesis, whereas L-arginine (Arg) and L-homoarginine (hArg) serve as substrates for NO synthesis. ADMA and other methylated arginines are...
6.
Tsikas D, Pham V, Suchy M, van de Ree M, Huisman M, Frolich J, et al.
Pharmacol Res
. 2015 Feb;
94:1-8.
PMID: 25662039
The present study describes the effects of atorvastatin on whole body synthesis of nitric oxide (NO), prostacyclin (PGI2), and thromboxane A2 (TxA2), on oxidative stress and nitrite/nitrate-related renal carbonic anhydrase...
7.
Kayacelebi A, Willers J, Pham V, Hahn A, Schneider J, Rothmann S, et al.
Amino Acids
. 2015 Jan;
47(9):1885-91.
PMID: 25618752
Elevated circulating concentrations of total L-homocysteine (thCys) and free asymmetric dimethylarginine (ADMA) are long-established cardiovascular risk factors. Low circulating L-homoarginine (hArg) concentrations were recently found to be associated with increased...
8.
Trettin A, Bohmer A, Suchy M, Probst I, Staerk U, Stichtenoth D, et al.
Oxid Med Cell Longev
. 2014 May;
2014:212576.
PMID: 24799980
Paracetamol (acetaminophen) is a widely used analgesic drug. It interacts with various enzyme families including cytochrome P450 (CYP), cyclooxygenase (COX), and nitric oxide synthase (NOS), and this interplay may produce...
9.
Schneider J, Pham V, Frolich J, Tsikas D
Exp Gerontol
. 2014 Mar;
55:159-60.
PMID: 24667122
No abstract available.
10.
Tsikas D, Frolich J, Klempnauer J, Becker T
Liver Transpl
. 2014 Mar;
20(6):744-5.
PMID: 24616179
No abstract available.