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Jure Leskovec

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Articles 84
Citations 4259
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Recent Articles
11.
Wang H, Fu T, Du Y, Gao W, Huang K, Liu Z, et al.
Nature . 2023 Aug; 621(7978):E33. PMID: 37648871
No abstract available.
12.
Roohani Y, Huang K, Leskovec J
Nat Biotechnol . 2023 Aug; 42(6):927-935. PMID: 37592036
Understanding cellular responses to genetic perturbation is central to numerous biomedical applications, from identifying genetic interactions involved in cancer to developing methods for regenerative medicine. However, the combinatorial explosion in...
13.
Wang H, Fu T, Du Y, Gao W, Huang K, Liu Z, et al.
Nature . 2023 Aug; 620(7972):47-60. PMID: 37532811
Artificial intelligence (AI) is being increasingly integrated into scientific discovery to augment and accelerate research, helping scientists to generate hypotheses, design experiments, collect and interpret large datasets, and gain insights...
14.
Hickey J, Becker W, Nevins S, Horning A, Perez A, Zhu C, et al.
Nature . 2023 Jul; 619(7970):572-584. PMID: 37468586
The intestine is a complex organ that promotes digestion, extracts nutrients, participates in immune surveillance, maintains critical symbiotic relationships with microbiota and affects overall health. The intesting has a length...
15.
Lu T, Brbic M, Park Y, Jackson T, Chen J, Kolluru S, et al.
Science . 2023 Jun; 380(6650):eadg0934. PMID: 37319212
Aging is characterized by a decline in tissue function, but the underlying changes at cellular resolution across the organism remain unclear. Here, we present the Aging Fly Cell Atlas, a...
16.
Fouladvand S, Gomez F, Nilforoshan H, Schwede M, Noshad M, Jee O, et al.
J Biomed Inform . 2023 Jun; 143:104407. PMID: 37271308
Objective: To determine whether graph neural network based models of electronic health records can predict specialty consultation care needs for endocrinology and hematology more accurately than the standard of care...
17.
Moor M, Banerjee O, Shakeri Hossein Abad Z, Krumholz H, Leskovec J, Topol E, et al.
Nature . 2023 Apr; 616(7956):259-265. PMID: 37045921
The exceptionally rapid development of highly flexible, reusable artificial intelligence (AI) models is likely to usher in newfound capabilities in medicine. We propose a new paradigm for medical AI, which...
18.
Rosen Y, Brbic M, Roohani Y, Swanson K, Li Z, Leskovec J
bioRxiv . 2023 Feb; PMID: 36778387
Analysis of single-cell datasets generated from diverse organisms offers unprecedented opportunities to unravel fundamental evolutionary processes of conservation and diversification of cell types. However, inter-species genomic differences limit the joint...
19.
Eyuboglu S, Zitnik M, Leskovec J
Pac Symp Biocomput . 2022 Dec; 28:61-72. PMID: 36540965
Biological networks are powerful representations for the discovery of molecular phenotypes. Fundamental to network analysis is the principle-rooted in social networks-that nodes that interact in the network tend to have...
20.
Brbic M, Cao K, Hickey J, Tan Y, Snyder M, Nolan G, et al.
Nat Methods . 2022 Oct; 19(11):1411-1418. PMID: 36280720
Accurate cell-type annotation from spatially resolved single cells is crucial to understand functional spatial biology that is the basis of tissue organization. However, current computational methods for annotating spatially resolved...