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Junwan Lu

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Articles 58
Citations 321
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Recent Articles
1.
Lu J, Zhang L, Yan C, Lin N, Zhang Y, Sha Y, et al.
Front Microbiol . 2025 Mar; 16:1473150. PMID: 40071199
Background: Multidrug-resistant strains of the genus can produce various β-lactamases that confer resistance to a broad spectrum of β-lactams, which poses a significant public health threat due to their emergence...
2.
Yu Y, Zhang R, Pan W, Sheng X, Chen S, Wang J, et al.
Front Microbiol . 2024 Dec; 15:1475172. PMID: 39726966
Background: The mechanisms underlying the resistance of the genus to aminoglycosides are complex, which poses a challenge for the efficient treatment of infectious diseases caused by these pathogens. To help...
3.
Lin N, Sha Y, Zhang G, Song C, Zhang Y, Zhao J, et al.
Front Cell Infect Microbiol . 2024 Aug; 14:1435123. PMID: 39139766
Background: Aminoglycoside-modifying enzymes (AMEs) play an essential role in bacterial resistance to aminoglycoside antimicrobials. With the development of sequencing techniques, more bacterial genomes have been sequenced, which has aided in...
4.
Zhang G, Zhang L, Sha Y, Chen Q, Lin N, Zhao J, et al.
Front Microbiol . 2023 Nov; 14:1229593. PMID: 37920263
Background: species have been identified as agents responsible for various diseases in both humans and animals. Multidrug-resistant strains pose a significant public health threat due to their emergence and spread...
5.
Zhang Y, Zhao J, Zhang G, Lin N, Sha Y, Lu J, et al.
Front Microbiol . 2023 Oct; 14:1252427. PMID: 37808287
Background: is a genus of gram-negative bacteria that can act as opportunistic pathogens. Recent studies have revealed that some species of show inherent resistance to β-lactams, but the resistance mechanisms...
6.
Sha Y, Lin N, Zhang G, Zhang Y, Zhao J, Lu J, et al.
Front Microbiol . 2023 Sep; 14:1224464. PMID: 37700861
Background: Aminoglycosides, as important clinical antimicrobials, are used as second-line drugs for treating multidrug-resistant tuberculosis or combined with β-lactam drugs for treating severe infections such as sepsis. Aminoglycoside-modifying enzyme (AME)...
7.
Zhao J, Zhang Y, Sha Y, Lin N, Zhang G, Lu J, et al.
Front Microbiol . 2023 Aug; 14:1222703. PMID: 37529328
Background: species of the family are well-known plant pathogens and animal and human conditional pathogens. Due to the widespread and continuous use of antimicrobials, multidrug-resistant strains continue to emerge, making...
8.
Lu J, Sha Y, Gao M, Shi W, Lin X, Li K, et al.
Front Microbiol . 2023 Jul; 14:1184349. PMID: 37455719
Background: , a species of genus of the family , exists widely in environments and habitats in various plants and worms, and occasionally causes human infections. This work aimed to...
9.
Sheng X, Lu W, Li A, Lu J, Song C, Xu J, et al.
Microbiol Spectr . 2023 Apr; 11(3):e0062023. PMID: 37039640
Aminoglycoside-modifying enzymes are among the most important mechanisms of resistance to aminoglycoside antibiotics, typically conferring high-level resistance by enzymatic drug inactivation. Previously, we isolated a multidrug-resistant Brucella intermedia strain ZJ499...
10.
Wang L, Zhu M, Yan C, Zhang Y, He X, Wu L, et al.
Front Microbiol . 2023 Mar; 14:985102. PMID: 36950157
Background: The emergence of highly drug-resistant , has become a major public health challenge. In this work, we aim to investigate the diversity of species and sequence types (STs) of...