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Junlei Chang

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Articles 67
Citations 2369
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Recent Articles
1.
Wei P, Lin K, Chen X, Fang C, Qiu L, Hu J, et al.
CNS Neurosci Ther . 2025 Mar; 31(3):e70306. PMID: 40075551
Aims: Alzheimer's disease (AD) involves a prolonged presymptomatic or preclinical stage with subtle pathological changes. Apolipoprotein E4 (APOE4) is a significant genetic risk factor for AD, yet its specific role...
2.
Qu Y, Cong M, Liu J, Zhang P, Shen Z, Zhang H, et al.
CNS Neurosci Ther . 2025 Mar; 31(3):e70323. PMID: 40035294
Aims: To investigate the characteristics of dynamic cerebral autoregulation (dCA) in patients after mechanical thrombectomy (MT) and the relationship between dCA and prognosis. Methods: In this prospective study, 89 and...
3.
Feng M, An Y, Qin Q, Fong I, Zhang K, Wang F, et al.
Cell Death Dis . 2024 Dec; 15(12):926. PMID: 39715736
Intracerebral hemorrhage (ICH) is a severe stroke subtype with high mortality and limited therapeutic options. The blood-brain barrier (BBB) breakdown post-ICH exacerbates secondary brain injury, highlighting the need for targeted...
4.
Gao J, Wei W, Ji C, Pan X, Chang J, Zhang Q, et al.
Animals (Basel) . 2024 Dec; 14(23). PMID: 39682320
The objective of this study was to investigate the effects of yucca extract (YE) supplementation on estrus, nutrient digestibility, antioxidant capacity and fecal microorganisms of gilts. Twenty gilts were randomly...
5.
Huang X, Wei P, Fang C, Yu M, Yang S, Qiu L, et al.
J Neuroinflammation . 2024 Oct; 21(1):265. PMID: 39427196
The blood-brain barrier (BBB) is a critical interface that maintains the central nervous system homeostasis by controlling the exchange of substances between the blood and the brain. Disruption of the...
6.
Yang H, Ibrahim M, Zhang S, Sun Y, Chang J, Qi H, et al.
Front Immunol . 2024 Aug; 15:1433590. PMID: 39139557
Salvianolic acid A (SalA), a bioactive compound extracted from Salvia miltiorrhiza, has garnered considerable interest for its potential in ameliorating the post-stroke neuroinflammation. This review delineates the possible molecular underpinnings...
7.
Cheng L, Li X, Li Y, Zhou H, Chen X, Chang J
Fitoterapia . 2024 Jul; 178:106143. PMID: 39053740
Four undescribed guaiane sesquiterpenes, aquisinenoids I-L (2-5) and five known compounds were isolated from the resins of Aquilaria sinensis. Their structures were deduced based on spectroscopic data analysis, X-ray crystallography...
8.
Suo S, Fang C, Liu W, Liu Q, Zhang Z, Chang J, et al.
Hum Genet . 2024 Jul; 143(8):939-953. PMID: 38969938
Unilateral moyamoya disease (MMD) represents a distinct subtype characterised by occlusive changes in the circle of Willis and abnormal vascular network formation. However, the aetiology and pathogenesis of unilateral MMD...
9.
Guo Z, Qu Y, Shen Z, Liu J, Wang Z, Sun Y, et al.
CNS Neurosci Ther . 2024 May; 30(5):e14748. PMID: 38727518
Aims: To investigate the characteristics of dynamic cerebral autoregulation (dCA) after intravenous thrombolysis (IVT) and assess the relationship between dCA and prognosis. Methods: Patients with unilateral acute ischemic stroke receiving...
10.
Feng Z, Fang C, Ma Y, Chang J
J Neuroinflammation . 2024 Apr; 21(1):110. PMID: 38678254
Obesity, a burgeoning global health issue, is increasingly recognized for its detrimental effects on the central nervous system, particularly concerning the integrity of the blood-brain barrier (BBB). This manuscript delves...