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Junkai Guo

Explore the profile of Junkai Guo including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 40
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Recent Articles
1.
Hou D, Zhou H, Tang Y, Liu Z, Su L, Guo J, et al.
Drug Des Devel Ther . 2025 Feb; 19:1043-1065. PMID: 39974609
Purpose: Cancer stands as a significant global public health concern, with traditional therapies potentially yielding severe side effects. Peptide-based cancer therapy is increasingly employed for diseases like cancer due to...
2.
Guo J, Wang X, Ni C, Wan X, Hu J
Nat Commun . 2022 May; 13(1):2752. PMID: 35585073
Direct deoxyazidation of alcohols with NaN is a straightforward method for the synthesis of widely used alkyl azides in organic chemistry. However, known methods have some limitations such as high...
3.
Zhao X, Dong R, Zhang L, Guo J, Shi Y, Ge L, et al.
Arthritis Res Ther . 2022 Feb; 24(1):37. PMID: 35120571
Background: Certain circRNAs could be used as biomarkers to determine the risk of development and/or severity of systemic lupus erythematosus, and their new function in the regulation of gene expression...
4.
You Y, Zhao X, Wu Y, Mao J, Ge L, Guo J, et al.
Front Immunol . 2021 Jul; 12:615859. PMID: 34220794
Purpose: Systemic lupus erythematosus (SLE) is a serious autoimmune disease. Its molecular pathogenesis, especially the long non-coding RNA (lncRNA) function, remains unclear. We want to investigate the lncRNA dysregulation profile...
5.
Guo J, Kuang C, Rong J, Li L, Ni C, Hu J
Chemistry . 2019 Mar; 25(30):7259-7264. PMID: 30869818
The deoxyfluorination of alcohols is a fundamentally important approach to access alkyl fluorides, and thus the development of shelf-stable, easy-to-handle, fluorine-economical, and highly selective deoxyfluorination reagents is highly desired. This...
6.
Xiao P, Rong J, Ni C, Guo J, Li X, Chen D, et al.
Org Lett . 2016 Dec; 18(22):5912-5915. PMID: 27934497
An atom-economical method for radical (phenylsulfonyl)difluoromethylation of isocyanides with PhSOCFH under transition-metal-free conditions has been developed. A PhSOCF radical is generated through the oxidation of PhSOCF after the deprotonation of...