June Penman
Overview
Explore the profile of June Penman including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
135
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Recent Articles
1.
Irving A, Abdulrazzaq G, Chan S, Penman J, Harvey J, Alexander S
Adv Pharmacol
. 2017 Aug;
80:223-247.
PMID: 28826536
Of the druggable group of G protein-coupled receptors in the human genome, a number remain which have yet to be paired with an endogenous ligand-orphan GPCRs. Among these 100 or...
2.
Haugh O, Penman J, Irving A, Campbell V
Curr Drug Targets
. 2016 Jan;
17(16):1834-1840.
PMID: 26758668
The classical endogenous cannabinoid (CB) system is composed of the endocannabinoid signalling molecules, 2-arachidonoyl glycerol (2-AG) and anandamide (AEA) and their G-protein coupled receptors (GPCR), CB1 and CB2 which together...
3.
Yrjola S, Parkkari T, Navia-Paldanius D, Laitinen T, Kaczor A, Kokkola T, et al.
Eur J Med Chem
. 2015 Nov;
107:119-32.
PMID: 26575458
To date, many known G protein-coupled receptor 55 (GPR55) ligands are those identified among the cannabinoids. In order to further study the function of GPR55, new potent and selective ligands...
4.
Henstridge C, Balenga N, Schroder R, Kargl J, Platzer W, Martini L, et al.
Br J Pharmacol
. 2010 Feb;
160(3):604-14.
PMID: 20136841
Background And Purpose: Although GPR55 is potently activated by the endogenous lysophospholipid, L-alpha-lysophosphatidylinositol (LPI), it is also thought to be sensitive to a number of cannabinoid ligands, including the prototypic...