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Jun-Pil Jang

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Articles 39
Citations 144
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Recent Articles
1.
Jang J, Roh J, Kim G, Park J, Hwang G, Park B, et al.
J Nat Prod . 2025 Feb; 88(2):433-439. PMID: 39902661
Two new polyketide-cyclic peptide hybrids jejupeptins A and B (), together with a known compound eurystatin B (), were isolated from a culture of sp. KCB15JA151. The chemical structures of...
2.
Hwang Y, Yoon H, Park H, Jang J, Park J, Park S, et al.
Int J Mol Sci . 2024 Sep; 25(18). PMID: 39337575
Sepsis is an inflammatory condition causing organ failure due to an uncontrolled immune response to infection and remains a significant challenge. Crotonis Semen has displayed various pharmacological effects, yet its...
3.
Kimishima A, Nishitomi A, Tsuruoka I, Sakai K, Hokari R, Honsho M, et al.
Biosci Biotechnol Biochem . 2024 Jul; 88(10):1212-1216. PMID: 38982331
In this paper, we describe our discovery of burnettiene A (1) as an antimalarial compound from the culture broth of Lecanicillium primulinum (current name: Flavocillium primulinum) FKI-6715 strain utilizing our...
4.
Kim M, Jeong D, Jang J, Jang J, Choi S
BMC Microbiol . 2024 Jun; 24(1):226. PMID: 38937695
Background: Bacterial antimicrobial resistance poses a severe threat to humanity, necessitating the urgent development of new antibiotics. Recent advances in genome sequencing offer new avenues for antibiotic discovery. Paenibacillus genomes...
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Roh J, Jang J, Oh T, Kim J, Lee B, Hong Y, et al.
Pharmacol Rep . 2024 Mar; 76(2):368-378. PMID: 38498259
Background: Excessive stress, a major problem in modern societies, affects people of all ages worldwide. Corticosterone is one of the most abundant hormones secreted during stressful conditions and is associated...
7.
Hwang Y, Lim J, Yoon H, Park S, Kim A, Jang J, et al.
Int J Mol Sci . 2024 Jan; 25(1). PMID: 38203555
Sepsis is a systemic inflammatory syndrome that results in multiple-organ failure caused by a dysregulated host immune response to microbial infection. Astragali complanati semen extract (ACSE) exhibits pharmacological activities, including...
8.
Heo K, Lee B, Hwang G, Park B, Jang J, Hwang B, et al.
Front Microbiol . 2023 Nov; 14:1274358. PMID: 38029143
The pluramycin family of natural products has diverse substituents at the C2 position, which are closely related to their biological activity. Therefore, it is important to understand the biosynthesis of...
9.
Han H, Sivaraman A, Kim M, Min K, Song M, Choi Y, et al.
J Adv Res . 2023 Nov; 64:67-81. PMID: 37977260
Introduction: Hypoxia-inducible factor 1 (HIF-1) is a transcriptional activator mediating adaptive responses to hypoxia. It is up-regulated in the tumor microenvironment and recognized as an effective anticancer drug target. Previously,...
10.
Hwang G, Roh J, Son S, Lee B, Jang J, Hur J, et al.
J Microbiol Biotechnol . 2023 Sep; 33(11):1437-1447. PMID: 37670557
A recently bioinformatic analysis of genomic sequences of fungi indicated that fungi are able to produce more secondary metabolites than expected. Despite their potency, many biosynthetic pathways are silent in...