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Jun-Jian Zhang

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Articles 37
Citations 459
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Recent Articles
11.
Yan F, Fan J, Huang Z, Zhang J
Cell Biosci . 2017 Jul; 7:33. PMID: 28670441
Background: Accumulating evidence demonstrates that the KRAB-ZNFs involve in various biological processes. As a typical member of KRAB-ZNFs, dysregulation of ZNF300 contributes to multiple pathologies such as leukemia and cancer....
12.
Hu Y, Yang Y, Zhang M, Deng M, Zhang J
J Nutr . 2017 May; 147(7):1437-1445. PMID: 28515159
Whether intermittent fasting (IF) pretreatment can prevent vascular cognitive dysfunction remains unknown to our knowledge. We investigated the effects and underlying mechanisms of IF pretreatment on cognitive dysfunction in a...
13.
Mei B, Liu G, Yang Y, Liu Y, Cao J, Zhang J
J Huazhong Univ Sci Technolog Med Sci . 2015 Dec; 35(6):885-890. PMID: 26670441
Based on the recently proposed Chinese ischemic stroke subclassification (CISS) system, intracranial branch atheromatous disease (BAD) is divided into large artery atherosclerosis (LAA) and penetrating artery disease (PAD). In the...
14.
Jin X, Ye F, Zhang J, Zhao Y, Zhou X
Neuropsychiatr Dis Treat . 2015 Jun; 11:1395-403. PMID: 26082636
Inflammation plays critical roles in the acute progression of the pathology of ischemic injury. Previous studies have shown that triptolide interferes with a number of pro-inflammatory mechanisms. In this study,...
15.
Liu H, Zhang J, Li X, Yang Y, Xie X, Hu K
Pharmacol Biochem Behav . 2015 May; 135:53-9. PMID: 26013850
Chronic cerebral hypoperfusion (CCH) has been commonly associated with Alzheimer's disease and other types of dementia, but therapies that can improve cerebral blood flow displayed little effect on impaired cognition....
16.
Zhang Q, Zhang J, Han Z
Int J Clin Exp Med . 2015 May; 8(2):2435-40. PMID: 25932185
This work aims to explore the efficacy of Rho kinase inhibitor Fasudil on cognitive impairment induced by chronic cerebral hypoperfusion in rats. A total of 32 male adult Sprague Dawley...
17.
Zhang H, Li L, Xu G, Mei Y, Zhang J, Murong S, et al.
J Huazhong Univ Sci Technolog Med Sci . 2014 Jun; 34(3):354-358. PMID: 24939298
Under global cerebral ischemia, the effect of different brain temperature on cerebral ischemic injury was studied. Male Sprague-Dawley rats were divided into normothermic (37-38°C) ischemia, mild hypothermic (31-32°C) ischemia, hyperthermic...
18.
Shu Y, Zhang H, Kang T, Zhang J, Yang Y, Liu H, et al.
PLoS One . 2013 Dec; 8(12):e81901. PMID: 24339978
Chronic cerebral hypoperfusion (CCH) is a common pathophysiological state that usually occurs in conditions such as vascular dementia and Alzheimer's disease, both of which are characterized by cognitive impairment. In...
19.
Xin J, Zhang J, Yang Y, Gao Y, Xiong L
Zhonghua Yi Xue Za Zhi . 2013 Oct; 93(21):1657-9. PMID: 24125677
Objective: To explore the association between estrogen receptor β (ERβ) gene polymorphisms and hypertension in postmenopausal women. Methods: The relationship of two polymorphisms (rs944050 and rs4986938) with hypertension was examined...
20.
Zhang H, Xiong R, Hujiken S, Zhang J, Zhang X
Chin Med J (Engl) . 2013 Sep; 126(18):3417-21. PMID: 24034081
Background: Dementia is a chronic progressive disease seriously affecting the patient's daily life and working skills and may cause the patient disability and dependence. Thus, caring for dementia patients inevitably...