Julius B Kirkegaard
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Explore the profile of Julius B Kirkegaard including associated specialties, affiliations and a list of published articles.
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27
Citations
860
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Recent Articles
1.
Kirkegaard J
Biol Methods Protoc
. 2024 Dec;
9(1):bpae084.
PMID: 39659670
Instance segmentation is the task of assigning unique identifiers to individual objects in images. Solving this task requires breaking the inherent symmetry that semantically similar objects must result in distinct...
2.
Himeoka Y, Kirkegaard J, Mitarai N, Krishna S
Sci Rep
. 2024 Sep;
14(1):22187.
PMID: 39333286
Understanding the relationship between the structure of chemical reaction networks and their reaction dynamics is essential for unveiling the design principles of living organisms. However, while some network-structural features are...
3.
Alonso A, Kirkegaard J
PNAS Nexus
. 2024 Jul;
3(7):pgae235.
PMID: 38952456
We investigate the boundary between chemotaxis driven by spatial estimation of gradients and chemotaxis driven by temporal estimation. While it is well known that spatial chemotaxis becomes disadvantageous for small...
4.
Alonso A, Kirkegaard J
Commun Biol
. 2023 Jul;
6(1):754.
PMID: 37468539
Computer-aided analysis of biological microscopy data has seen a massive improvement with the utilization of general-purpose deep learning techniques. Yet, in microscopy studies of multi-organism systems, the problem of collision...
5.
Beilharz K, Kragh K, Fritz B, Kirkegaard J, Tolker-Nielsen T, Bjarnsholt T, et al.
STAR Protoc
. 2023 May;
4(2):102269.
PMID: 37133990
Here, we present a protocol for assessing metabolic activity of bacterial populations by measuring heat flow using isothermal calorimetry. We outline the steps for preparing the different growth models of...
6.
Skjegstad L, Nickels J, Sneppen K, Kirkegaard J
Biophys J
. 2023 Apr;
122(12):2421-2429.
PMID: 37085994
Gene expression states are often stably sustained in cis despite massively disruptive events like DNA replication. This is achieved by on-going enzymatic activity that maintains parts of the DNA in...
7.
Kirkegaard J, Sneppen K
Phys Rev E
. 2022 Dec;
106(5-1):054409.
PMID: 36559503
Exploiting the mathematical curiosity of intransitive dice, we present a simple theoretical model for coevolution that captures scales ranging from the genome of the individual to the system-wide emergence of...
8.
Lichtenberg M, Kragh K, Fritz B, Kirkegaard J, Tolker-Nielsen T, Bjarnsholt T
Cell Rep
. 2022 Oct;
41(3):111515.
PMID: 36260996
Bacteria in biofilms are embedded in extracellular matrix and display low metabolic activity, partly due to insufficient diffusive exchange of metabolic substrate. The extracellular matrix and low metabolic activity both...
9.
Kirkegaard J
BMC Bioinformatics
. 2022 May;
23(1):191.
PMID: 35597909
Background: The initial step in comparing mathematical models to experimental data is to do a fit. This process can be complicated when either the mathematical models are not analytically solvable...
10.
Fritz B, Kirkegaard J, Nielsen C, Kirketerp-Moller K, Malone M, Bjarnsholt T
APMIS
. 2022 May;
130(8):524-534.
PMID: 35567538
Clinicians and researchers utilize subjective, clinical classification systems to stratify lower extremity ulcer infections for treatment and research. The purpose of this study was to examine whether these clinical classifications...