Julio Cesar Fernandes
Overview
Explore the profile of Julio Cesar Fernandes including associated specialties, affiliations and a list of published articles.
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13
Citations
130
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Recent Articles
1.
Martinez Junior A, Lima A, Martins G, Tiera V, Benderdour M, Fernandes J, et al.
Mar Drugs
. 2022 Jul;
20(8).
PMID: 35892944
Nowadays, the therapeutic efficiency of small interfering RNAs (siRNA) is still limited by the efficiency of gene therapy vectors capable of carrying them inside the target cells. In this study,...
2.
Rosa F, Fernandes J, Delisle J, Ranger P, Albano M, Stieven Filho E
J Orthop Surg Res
. 2022 Feb;
17(1):112.
PMID: 35184759
Background: Injuries to the articular cartilage of the knee often fail to heal properly due to the hypocellular and avascular nature of this tissue. Subsequent disability can limit participation in...
3.
Rondon E, Benabdoun H, Vallieres F, Segalla Petronio M, Tiera M, Benderdour M, et al.
Int J Nanomedicine
. 2020 Sep;
15:6183-6200.
PMID: 32922001
Purpose: Diethylaminoethyl-chitosan (DEAE-CH) is a derivative with excellent potential as a delivery vector for gene therapy applications. The aim of this study is to evaluate its toxicological profile for potential...
4.
de Souza R, Picola I, Shi Q, Segalla Petronio M, Benderdour M, Fernandes J, et al.
Int J Biol Macromol
. 2018 Jul;
119:186-197.
PMID: 30031084
Chitosan has been indicated as a promising carrier for the preparation of small interfering RNA (siRNA) delivery systems due to its remarkable properties. However, its weak interactions with siRNA molecules...
5.
Shi Q, Rondon-Cavanzo E, Picola I, Tiera M, Zhang X, Dai K, et al.
Int J Nanomedicine
. 2018 Feb;
13:387-402.
PMID: 29391796
Background: Tumor necrosis factor-alpha (TNFα), a pro-inflammatory cytokine, has been shown to play a role in the pathophysiology of rheumatoid arthritis. Silencing TNFα expression with small interfering RNA (siRNA) is...
6.
Picola I, Shi Q, Fernandes J, Segalla Petronio M, Lima A, Tiera V, et al.
J Biomater Sci Polym Ed
. 2016 Aug;
27(16):1611-30.
PMID: 27532422
The purpose of this work was to improve the functional properties of chitosan for gene transfer by inserting phosphorylcholine (PC) and diethylaminoethyl (DEAE) groups into the main chain. A series...
7.
de Paula Pansani Oliveira F, Picola I, Shi Q, Barbosa H, Tiera V, Fernandes J, et al.
Nanotechnology
. 2013 Jan;
24(5):055101.
PMID: 23306549
Chitosan has been indicated as a safe and promising polycation vector for gene delivery. However its low transfection efficiency has been a challenging obstacle for its application. To address this...
8.
Case A, Picola I, Zaniquelli M, Fernandes J, Taboga S, Winnik F, et al.
J Colloid Interface Sci
. 2009 May;
336(1):125-33.
PMID: 19446829
The interactions between phosphorylcholine-substituted chitosans (PC-CH) and calf-thymus DNA (ct-DNA) were investigated focusing on the effects of the charge ratio, the pH, and phosphorylcholine content on the size and stability...
9.
Blouin J, Dragomir A, Moride Y, Ste-Marie L, Fernandes J, Perreault S
Br J Clin Pharmacol
. 2008 May;
66(1):117-27.
PMID: 18460036
Aims: To evaluate the association between noncompliance with alendronate and risedronate and the risk of nonvertebral osteoporotic fracture in community-dwelling elderly women. Methods: A nested case-control study was conducted using...
10.
Perreault S, Dragomir A, Blais L, Moride Y, Rossignol M, Ste-Marie L, et al.
Pharmacoepidemiol Drug Saf
. 2008 Jan;
17(3):248-59.
PMID: 18213734
Aim: Evidence supports bone-specific drugs (BSDs) efficacy in the fracture risk reduction. But treatment rates for osteoporosis among high-risk patients are far below the recommended guidelines. A major concern about...