Julieta M Acevedo
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Explore the profile of Julieta M Acevedo including associated specialties, affiliations and a list of published articles.
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9
Citations
174
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Recent Articles
1.
Acevedo J, Hoermann B, Schlimbach T, Teleman A
Sci Rep
. 2018 Mar;
8(1):4018.
PMID: 29507361
The sequence context surrounding the AUG start codon of an open reading frame - the 'Kozak sequence' - affects the probability with which a scanning ribosome will recognize the start...
2.
Melani M, Valko A, Romero N, Aguilera M, Acevedo J, Bhujabal Z, et al.
Mol Biol Cell
. 2017 Sep;
28(22):3070-3081.
PMID: 28904211
Autophagy is an evolutionary conserved process by which eukaryotic cells undergo self-digestion of cytoplasmic components. Here we report that a novel immunophilin, which we have named Zonda, is critically required...
3.
Schleich S, Acevedo J, von Hohenberg K, Teleman A
Sci Rep
. 2017 Jun;
7(1):3722.
PMID: 28623304
The non-canonical initiation factors DENR and MCTS1 have been linked to cancer and autism. We recently showed in Drosophila that DENR and MCTS1 regulate translation re-initiation on transcripts containing upstream...
4.
Bertolin A, Katz M, Yano M, Pozzi B, Acevedo J, Blanco-Obregon D, et al.
Nucleic Acids Res
. 2016 May;
44(16):7555-67.
PMID: 27141964
Adaptation to hypoxia depends on a conserved α/β heterodimeric transcription factor called Hypoxia Inducible Factor (HIF), whose α-subunit is regulated by oxygen through different concurrent mechanisms. In this study, we...
5.
Katz M, Acevedo J, Wappner P
Fly (Austin)
. 2014 Dec;
8(3):153-6.
PMID: 25482726
In this Extra View we comment on our recent work on Sudestada1 (Sud1), a Drosophila 2-oxoglutarate (2OG)-dependent dioxygenase that belongs to the Ribosomal Oxygenase (ROX) subfamily. Sud1 is required for...
6.
Katz M, Acevedo J, Loenarz C, Galagovsky D, Liu-Yi P, Perez-Pepe M, et al.
Proc Natl Acad Sci U S A
. 2014 Feb;
111(11):4025-30.
PMID: 24550463
Genome sequences predict the presence of many 2-oxoglutarate (2OG)-dependent oxygenases of unknown biochemical and biological functions in Drosophila. Ribosomal protein hydroxylation is emerging as an important 2OG oxygenase catalyzed pathway,...
7.
Galagovsky D, Katz M, Acevedo J, Sorianello E, Glavic A, Wappner P
Mol Biol Cell
. 2014 Jan;
25(6):916-24.
PMID: 24430872
Mammalian insulin-degrading enzyme (IDE) cleaves insulin, among other peptidic substrates, but its function in insulin signaling is elusive. We use the Drosophila system to define the function of IDE in...
8.
Perez-Perri J, Acevedo J, Wappner P
Int J Mol Sci
. 2011 Aug;
12(7):4705-21.
PMID: 21845106
Reduction in oxygen levels below normal concentrations plays important roles in different normal and pathological conditions, such as development, tumorigenesis, chronic kidney disease and stroke. Organisms exposed to hypoxia trigger...
9.
Acevedo J, Centanin L, Dekanty A, Wappner P
PLoS One
. 2010 Sep;
5(8):e12390.
PMID: 20811646
Background: The Hypoxia Inducible Factor (HIF) mediates cellular adaptations to low oxygen. Prolyl-4-hydroxylases are oxygen sensors that hydroxylate the HIF alpha-subunit, promoting its proteasomal degradation in normoxia. Three HIF-prolyl hydroxylases,...