Julien Puyal
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Explore the profile of Julien Puyal including associated specialties, affiliations and a list of published articles.
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7872
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Recent Articles
1.
Milano G, Reinero M, Puyal J, Tozzi P, Samaja M, Porte-Thome F, et al.
J Am Heart Assoc
. 2025 Mar;
:e036859.
PMID: 40055146
Background: Life-threatening pulmonary arterial hypertension (PAH) still lacks a direct therapeutic approach targeted to the molecular defects associated with the disease. Here, we focus on the impaired regulation of intracellular...
2.
Neuronal autosis: the self-destructive side of autophagy involved in hypoxic-ischemic neuronal death
Ginet V, Depierre P, Puyal J
Neural Regen Res
. 2024 Nov;
PMID: 39589723
No abstract available.
3.
Ginet V, Puyal J, Truttmann A
Pediatr Res
. 2024 Jul;
96(5):1120-1122.
PMID: 39014242
No abstract available.
4.
Depierre P, Ginet V, Truttmann A, Puyal J
Cell Death Dis
. 2024 May;
15(5):363.
PMID: 38796484
Macroautophagy (hereafter called autophagy) is an essential physiological process of degradation of organelles and long-lived proteins. The discovery of autosis, a Na/K-ATPase (ATP1)-dependent type of autophagic cell death with specific...
5.
Rosenberg N, Reva M, Binda F, Restivo L, Depierre P, Puyal J, et al.
Glia
. 2022 Dec;
71(4):957-973.
PMID: 36537556
Alzheimer's disease (AD) is becoming increasingly prevalent worldwide. It represents one of the greatest medical challenges as no pharmacologic treatments are available to prevent disease progression. Astrocytes play crucial functions...
6.
Briquet M, Rocher A, Alessandri M, Rosenberg N, de Castro Abrantes H, Wellbourne-Wood J, et al.
J Cereb Blood Flow Metab
. 2022 Mar;
42(9):1650-1665.
PMID: 35240875
Lactate can be used by neurons as an energy substrate to support their activity. Evidence suggests that lactate also acts on a metabotropic receptor called HCAR1, first described in the...
7.
Trofimenko E, Grasso G, Heulot M, Chevalier N, Deriu M, Dubuis G, et al.
Elife
. 2021 Oct;
10.
PMID: 34713805
Cell-penetrating peptides (CPPs) allow intracellular delivery of bioactive cargo molecules. The mechanisms allowing CPPs to enter cells are ill-defined. Using a CRISPR/Cas9-based screening, we discovered that KCNQ5, KCNN4, and KCNK5...
8.
Thiebaut A, Buendia I, Ginet V, Lemarchand E, Boutagouga Boudjadja M, Hommet Y, et al.
Autophagy
. 2021 Sep;
18(6):1297-1317.
PMID: 34520334
Cerebral ischemia is a pathology involving a cascade of cellular mechanisms, leading to the deregulation of proteostasis, including macroautophagy/autophagy, and finally to neuronal death. If it is now accepted that...
9.
Klionsky D, Abdel-Aziz A, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, et al.
Autophagy
. 2021 Feb;
17(1):1-382.
PMID: 33634751
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our...
10.
Truttmann A, Ginet V, Puyal J
Front Cell Dev Biol
. 2020 Mar;
8:27.
PMID: 32133356
Despite tremendous advances in neonatal intensive care over the past 20 years, prematurity carries a high burden of neurological morbidity lasting lifelong. The term encephalopathy of prematurity (EoP) coined by...