Julie C Watt
Overview
Explore the profile of Julie C Watt including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
721
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0
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Recent Articles
1.
Ruvolo P, Zhou L, Watt J, Ruvolo V, Burks J, Jiffar T, et al.
J Cell Biochem
. 2011 Mar;
112(6):1696-707.
PMID: 21360576
Recent studies in acute myeloid leukemia (AML) suggest activation of pro-proliferative signaling cascades including those mediated by protein kinase C (PKC) represent a poor prognostic factor for patients. The classical...
2.
Tsao T, Kornblau S, Safe S, Watt J, Ruvolo V, Chen W, et al.
Cancer Res
. 2010 May;
70(12):4949-60.
PMID: 20501850
Peroxisome proliferator-activated receptor-gamma (PPARgamma) is a member of the nuclear receptor (NR) family of transcription factors with important regulatory roles in cellular growth, differentiation, and apoptosis. Using proteomic analysis, we...
3.
Samudio I, Duvvuri S, Clise-Dwyer K, Watt J, Mak D, Kantarjian H, et al.
Leuk Lymphoma
. 2010 Apr;
51(5):911-919.
PMID: 20423286
Non-mutational inactivation of p53 is frequent in acute myeloid leukemia (AML) via overexpression of MDM2. We report that treatment with MI-63, a novel inhibitor of MDM2, activates p53 signaling to...
4.
Nica A, Tsao C, Watt J, Jiffar T, Kurinna S, Jurasz P, et al.
Cell Cycle
. 2008 Oct;
7(21):3362-70.
PMID: 18948750
Ceramide is a sphingolipid that activates stress kinases such as p38 and c-JUN N-Terminal Kinase (JNK). Though Chronic Myelogenous Leukemia (CML) derived K562 cells resist killing by short chain C2-ceramide,...
5.
Tabe Y, Konopleva M, Kondo Y, Contractor R, Tsao T, Konoplev S, et al.
Cancer Biol Ther
. 2007 Dec;
6(12):1967-77.
PMID: 18075297
Acute promyelocytic leukemia (APL) is associated with oncogenic PML-RARalpha that acts as a dominant negative transcriptional repressor of retinoic acid (RA) receptor target genes by recruiting histone deacetylase (HDAC). The...
6.
Koschmieder S, DAlo F, Radomska H, Schoneich C, Chang J, Konopleva M, et al.
Blood
. 2007 Aug;
110(10):3695-705.
PMID: 17671235
2-Cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) induces differentiation and apoptosis of tumor cells in vitro and in vivo. Here we assessed the effects of CDDO on CCAAT enhancer-binding protein alpha (CEBPA), a transcription...
7.
Konopleva M, Contractor R, Tsao T, Samudio I, Ruvolo P, Kitada S, et al.
Cancer Cell
. 2006 Nov;
10(5):375-88.
PMID: 17097560
BCL-2 proteins are critical for cell survival and are overexpressed in many tumors. ABT-737 is a small-molecule BH3 mimetic that exhibits single-agent activity against lymphoma and small-cell lung cancer in...
8.
Moore L, Venkatachalam S, Vogel H, Watt J, Wu C, Steinman H, et al.
Oncogene
. 2003 Oct;
22(49):7831-7.
PMID: 14586409
The p19ARF gene product responds to oncogenic stresses by interfering with the inhibitory effects of Mdm2 on p53, thus enhancing p53 activity and its antiproliferative functions. The absence of p19ARF...
9.
Gatza M, Watt J, Marriott S
Oncogene
. 2003 Aug;
22(33):5141-9.
PMID: 12910251
The human T-cell leukemia virus type I (HTLV-I) is an oncogenic retrovirus that is responsible for adult T-cell leukemia and a neurological disease, HTLV-I-associated myelopathy/tropical spastic paraparesis. HTLV-I encodes an...