Juliane Schwarz
Overview
Explore the profile of Juliane Schwarz including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
327
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Recent Articles
1.
Garg G, Dienemann C, Farnung L, Schwarz J, Linden A, Urlaub H, et al.
Mol Cell
. 2023 Jun;
83(14):2464-2477.e5.
PMID: 37369200
Co-transcriptional capping of the nascent pre-mRNA 5' end prevents degradation of RNA polymerase (Pol) II transcripts and suppresses the innate immune response. Here, we provide mechanistic insights into the three...
2.
Rengachari S, Schilbach S, Kaliyappan T, Gouge J, Zumer K, Schwarz J, et al.
Nat Struct Mol Biol
. 2022 Nov;
29(12):1159-1169.
PMID: 36424526
RNA polymerase II (Pol II) carries out transcription of both protein-coding and non-coding genes. Whereas Pol II initiation at protein-coding genes has been studied in detail, Pol II initiation at...
3.
Maciej V, Mateva N, Schwarz J, Dittmers T, Mallick M, Urlaub H, et al.
Nucleic Acids Res
. 2022 Sep;
50(18):10665-10679.
PMID: 36130271
The RNA-binding protein tristetraprolin (TTP) is a potent activator of mRNA decay, specifically for transcripts bearing AU-rich elements (AREs) in their 3'-untranslated regions. TTP functions as a mediator for mRNA...
4.
Moll A, Ramirez L, Ninov M, Schwarz J, Urlaub H, Zweckstetter M
Nat Commun
. 2022 Jun;
13(1):3668.
PMID: 35760815
Alzheimer's disease is a neurodegenerative disorder in which misfolding and aggregation of pathologically modified Tau is critical for neuronal dysfunction and degeneration. The two central chaperones Hsp70 and Hsp90 coordinate...
5.
Gowravaram M, Schwarz J, Khilji S, Urlaub H, Chakrabarti S
Nat Commun
. 2019 Nov;
10(1):5054.
PMID: 31699982
The mammalian Staufen proteins (Stau1 and Stau2) mediate degradation of mRNA containing complex secondary structures in their 3'-untranslated region (UTR) through a pathway known as Staufen-mediated mRNA decay (SMD). This...
6.
Schwarz J, Bringmann H
Elife
. 2017 Mar;
6.
PMID: 28244369
Sleep is a behavior that is found in all animals that have a nervous system and that have been studied carefully. In larvae, sleep is associated with a turning behavior,...
7.
Malecki J, Aileni V, Ho A, Schwarz J, Moen A, Sorensen V, et al.
Nucleic Acids Res
. 2017 Jan;
45(8):4370-4389.
PMID: 28108655
Lysine methylation is abundant on histone proteins, representing a dynamic regulator of chromatin state and gene activity, but is also frequent on many non-histone proteins, including eukaryotic elongation factor 1...
8.
Lecanda A, Nilges B, Sharma P, Nedialkova D, Schwarz J, Vaquerizas J, et al.
Methods
. 2016 Jul;
107:89-97.
PMID: 27450428
Protein translation is at the heart of cellular metabolism and its in-depth characterization is key for many lines of research. Recently, ribosome profiling became the state-of-the-art method to quantitatively characterize...
9.
Rao J, Pfeiffer M, Frank S, Adachi K, Piccini I, Quaranta R, et al.
Cell Stem Cell
. 2016 Apr;
18(4):554-6.
PMID: 27058939
No abstract available.
10.
Rao J, Pfeiffer M, Frank S, Adachi K, Piccini I, Quaranta R, et al.
Cell Stem Cell
. 2016 Jan;
18(3):341-53.
PMID: 26748419
Cardiac induction requires stepwise integration of BMP and WNT pathway activity. Human embryonic stem cells (hESCs) are developmentally and clinically relevant for studying the poorly understood molecular mechanisms downstream of...