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Juliana Oliveira de Souza

Explore the profile of Juliana Oliveira de Souza including associated specialties, affiliations and a list of published articles. Areas
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Citations 32
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Recent Articles
1.
Luczywo A, Gonzalez L, Aguiar A, Oliveira de Souza J, Souza G, Oliva G, et al.
Nat Prod Res . 2021 Mar; 36(15):3887-3893. PMID: 33703954
Malaria is an infectious illness, affecting vulnerable populations in Third World countries. Inspired by natural products, indole alkaloids have been used as a nucleus to design new antimalarial drugs. So,...
2.
de Souza G, Bueno R, Oliveira de Souza J, Zanini C, Cruz F, Oliva G, et al.
Malar J . 2020 Jan; 18(1):447. PMID: 31888654
Background: Artemisinin-based combination therapy (ACT) is used as the first-line treatment of uncomplicated malaria caused by the Plasmodium falciparum parasite and chloroquine-resistant Plasmodium vivax parasites. Evidence of resistance to ACT...
3.
Dawson A, Trumper P, Oliveira de Souza J, Parker H, Jones M, Hales T, et al.
IUCrJ . 2019 Nov; 6(Pt 6):1014-1023. PMID: 31709057
Protein-engineering methods have been exploited to produce a surrogate system for the extracellular neurotransmitter-binding site of a heteromeric human ligand-gated ion channel, the glycine receptor. This approach circumvents two major...
4.
Okada-Junior C, Monteiro G, Aguiar A, Batista V, Oliveira de Souza J, Souza G, et al.
ACS Omega . 2019 Aug; 3(8):9424-9430. PMID: 31459076
We describe herein the design and synthesis of -phenyl phthalimide derivatives with inhibitory activities against (sensitive and resistant strains) in the low micromolar range and noticeable selectivity indices against human...
5.
Oliveira de Souza J, Dawson A, Hunter W
ChemMedChem . 2017 Mar; 12(8):577-579. PMID: 28333400
The natural product acivicin inhibits the glutaminase activity of cytidine triphosphate (CTP) synthetase and is a potent lead compound for drug discovery in the area of neglected tropical diseases, specifically...